Fight for NFC Playoff Seeding: Cowboys vs Cardinals Week 17 Predictions Preview, Odds & Trends


The 10-5 Cardinals head to Dallas to take on the 11-4 Cowboys

Cardinals vs Cowboys Preview

The Arizona Cardinals and Dallas Cowboys are two teams on different paths heading into the playoffs. Dallas is on a four-game win streak, and they have a three-game lead over the Philadelphia Eagles for the NFC East. Arizona has lost three consecutive games, conceding their lead in the NFC West to the Los Angeles Rams last Sunday.

The Cardinals are in the midst of losing 4 straight with a trip to Dallas to play a tough Cowboys team. The Cowboys defense has been one of the best in the NFL, lead by Trevon Diggs who leads the league in interceptions (11). The defensive line has also caused opponents troubles this season, led by standout rookie Micah Parsons. Parsons has an impressive 13 sacks on the year.

Arizona has been in an offensive funk over the last couple weeks, with Kyler Murray having to find different ways to get his teammates involved. The “run-and-gun” has worked well for the Cardinals but has seen regression during the losing streak. Penalties have been drive killers for the Arizona’s offense but also the level of competition has been harder during the back-half of the season.

This season can not go by without an unfortunate mention of Covid-19. Teams all over the league have been suffering players around and Arizona have some big holes due to missing key starters. Running back James Conner, wide receiver Rondale Moore, and defensive lineman Jordan Phillips are all looking to come back off the Covid list.

The Cowboys have been able to avoid significant COVID-19 issues this season. They’ve had positive cases, but they have not had the kind of outbreak that has decimated teams like the Ravens and Saints. Covid will be a storyline has we head into the playoffs, hopefully teams will be able to survive having key players out in critical games.

Cardinals vs Cowboys Odds


  • Cardinals +5.5 (-110) / Cowboys -5.5 (-110)


  • Cardinals +195 / Cowboys -240


  • 49 (Over -110/Under -110)

Cardinals vs Cowboys Trends

  • Arizona are 2-4 against the spread (ATS) in their last six games. 
  • The Cardinals are 10-5 straight up (SU) in their last 15 games. 
  • Arizona are 5-1 ATS in their last six games against the Cowboys. 
  • The Cardinals are 5-1 SU in their last six games against the Cowboys. 
  • The Cardinals are 7-1 ATS in their last 8 road games. 
  • The UNDER is 7-2 in the Cowboys’ last nine games. 
  • The UNDER is 8-4 in the last 12 games against these two teams. 
  • The Cowboys are 4-1 ATS in their last five games. 

Both of these teams have found success against the spread (ATS) this season. Dallas boasts a league-best 12-3 ATS record, while Arizona sits at 9-6.

NFL Computer Predictions: Arizona Cardinals vs Dallas Cowboys

For the latest computer picks on the Arizona Cardinals vs Dallas Cowboys, along with every other NFL game, check out my weekly NFL Football Game Matchups. Straight-up computer projections, ATS projections, public consensus betting data, even scoring forecasts that can help with Over/Under betting.

These computer-derived matchups do NOT represent my official picks, as there is a lot more analysis required (injuries, trends, situations and other technical analysis). If you want my full analysis, detailed write-ups, and official picks, be sure to get my email newsletter.

Sunday’s computer projections for Week 17:

Arizona Cardinals: 22.410 points (31% likely to win SU)

Dallas Cowboys: 29.930 points (65% likely to win SU)

The computer gives an edge to the Cowboys and leans UNDER the current posted total. Check the latest NFL odds here and don’t miss my premium Week 17 NFL picks.