San Francisco at Arizona

Arizona has split four games since Kyler Murray's return, including a 24-10 victory at Pittsburgh two weeks ago before the bye. San Francicso won the first meeting 35-16 on Oct. 1 when Murray was still out. Murray has thrown for 864 yards on a 60.8 percent completion rate with three TDs and two interceptions since returning to the lineup. James Connor has 631 rushing yards on 4.9 yards per carry. The 49ers are just 3-4 ATS their past seven games and didn't cover while defeating Seattle 28-16 as a 16.5-point favorite and the game stayed UNDER. Arizona went UNDER by three points against the Steelers and the Cardinals are 5-3 UNDER their past eight games. Arizona has covered four straight against teams with winning road records and it is 7-2-1 ATS its past 10 games after allowing fewer than 15 points its previous game. The Cardinals are 6-2 UNDER following a bye week and they have gone UNDER five of their past six December games. Take the Cardinals and the UNDER.