Tampa Bay at New Orleans

These two rivals meet for the first time this season, and the current trend has seen the underdog cover four straight. Tampa Bay has had trouble with New Orleans, losing all four regular-season meetings since Tom Brady came to the Bucs. In those four games, Brady was sacked 13 times, lost two fumbles, had six TDs and eight interceptions. Tampa scored an average of just 13.2 PPG in those losses while averaging 32.3 against the rest of the league. The Buccaneers had an easy opener after Dak Prescott was injured, but they're 2-7 ATS after a win of 14 or points. With Brady, the team is also 18-3 OVER when both teams score more than 20 points, and they'll need to step on the gas to help stop this slide against the Saints. New Orleans didn't play a great game in the opener but still managed to win 27-26 at Atlanta, so this is their home opener. The ground attack had 179 yards while QB Jameis Winston had two TDs, no picks, and 269 yards. NFL home teams like New Orleans off of a victory vs. a division rival are 39-14 ATS in a game featuring two teams that had winning records in the previous season. New Orleans on a 7-1 spread run against the Bucs, including 5-2 ATS in this stadium. Tampa is on a 7-0 run OVER following a double-digit road win, and those games sailed over the number by 9.2 PPG. Play New Orleans to cover and take this game to go OVER the total.