San Francisco at Seattle

Seattle won six of its final eight games in 2024, but now has a new starting quarterback in Sam Darnold, who unexpectedly had a breakout season with the Vikings before signing with the Seahawks. Granted, he had a superstar receiver in Justin Jefferson, but he now has talented targets in Jaxon Smith-Njigba and Super Bowl MVP Cooper Kupp. Darnold threw for 4,319 yards and 35 TDs with just 12 interceptions last year. The defense returns 10 starters after finishing the season strong. Seattle has covered four of six as an underdog. San Francisco was a money burner, finishing 1-8 ATS in its last nine games and losing seven of eight outright. The 49ers are 0-5 ATS in their past five road games, 1-6 ATS overall against NFC teams. Seattle is 7-1 UNDER as a home underdog of 0.5-3.0 points. San Francisco is 9-2 UNDER its past 11 games in Week 1. Take the Seahawks and the UNDER.