Pittsburgh at Buffalo

Buffalo is sitting Josh Allen for this one, and head coach Joe Brady has been vague about which other starters will even see the field, citing a short week off a joint practice and last Saturday's game. Kyle Allen is set to take the bulk of the snaps behind center for the Bills. Pittsburgh is going the other direction: new head coach Mike McCarthy has already ruled out both Aaron Rodgers and Mason Rudolph, turning this game over entirely to Will Howard and Drew Allar, the two young arms competing for a roster spot behind Rodgers. That is a real audition on one sideline and a light rehearsal on the other, and it shapes how this one should play out. Pittsburgh's kids have every incentive to sling it and make a case for a 53-man spot two days out from cutdowns, while Buffalo's lineup is thinner on continuity than the name at the top of the depth chart suggests. Backup-heavy football in the preseason finale tends to play loose: more busted coverages, more broken tackles, drives that stall out instead of getting stopped. That combination points in the same direction on both bets. Take Pittsburgh on the moneyline and take the OVER.