New Orleans at Carolina

Jameis Winston had the game of his life in Week 1 with 5 TDs and no picks, but do you believe he's suddenly turned a corner and turned into an elite QB? Let's not overreact. In his previous two years as a starter from 2018-19, Winston threw 19 TDs with 14 interceptions, then 33 TDs and 30 picks. Throw in 22 fumbles in 40 starts from 2017-19, and he's been a turnover machine most of his career. The opener was at "home," and New Orleans is 5-13 ATS on the road in the first two weeks of the season, and they are on a 1-6 ATS run against winning teams. Carolina plays its second straight home game and looked good in the opener, topping the Jets with excellent balance (270 passing yards and 111 rushing). The Panthers are 33-18 ATS at home off a non-conference game, and six of the last 11 regular-season meetings between these division rivals have been decided by three points or fewer with the underdog 11-3 ATS. Play Carolina.