This Pro Pick was released to clients on October 18, 2025 at 10:28AM ET.
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Los Angeles vs. Jacksonville

October 19, 2025
img9:30 AM Eastern

London calling. Expect the Rams to answer with a victory against the Jaguars in this London matchup. Both teams are 4-2 SU and ATS, but that is where the similarity ends. The Rams reached the divisional playoffs, where they lost to the Super Bowl champion Eagles last season. They should be 5-1 this season, but one of their losses came to the Eagles on a blocked field goal to end the game. Jacksonville last made the playoffs in 2022 and is coming off an 8-point home loss to the Seahawks. Los Angeles quarterback Matthew Stafford has a passer rating of 106.2 with a 12-to-2 touchdown-to-interception ratio. Jacksonville quarterback Trevor Lawrence has an 81.9 passer rating with an 8-to-5 touchdown-to-interception ratio. Not only do the Rams have the more accomplished quarterback, but they also have the superior defense. The Rams give up fewer yards per play and fewer completions than Jacksonville. The Jaguars will also be without injured linebacker Devin Lloyd, the AFC Defensive Player of the Month for September. Lawrence was sacked a season-high seven times against Seattle. The Rams' defense ranks in the top five in pressures and the top eight in pressure rate during the first six weeks. Rams defensive lineman Byron Young ranks second in the NFL with 7.5 sacks. Teammate Jared Verse has nine quarterback hits in the past two weeks. That is bad news for Jacksonville's offensive tackles, Walker Little and Anton Harrison, who had it rough against the Seahawks last week. Take the Rams on the moneyline.

1 unit on Los Angeles -148 (moneyline) (risk 1 to return 1.68)
Result:
WIN
FINAL
1
2
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F
Los Angeles Rams img
14
7
0
14
35
Jacksonville Jaguars
0
0
0
7
7
consensus consensus
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