Los Angeles at Seattle

Seattle comes home for its opener, and this team is an absolute beast at Century Link Field in the postseason, regular season and preseason - especially for hard-driving coach Pete Carroll, who is 22-11 ATS in August. This team has loads of depth and talent, especially on defense, and even in losing to the high-powered Broncos last week, they only allowed 274 yards. On offense, their preseason QB rotation is loaded with three players who have a lot of NFL regular season starting experience in Russell Wilson, Tarvaris Jackson and Terrelle Pryor. Coach Carroll demands physical play - and gets it. San Diego is in town for their first road game with nothing to prove after a 27-7 rout of Dallas. A year ago in week two in their first road game, the Chargers turned it over four times in a loss at Chicago, surrendering 33 points. These teams met early last August too, and the Seahawks won in San Diego 31-10, as part of a 4-1 SU/ATS Seattle preseason run. Go with the defending champs at home.