These Pro Picks were released to clients on October 06, 2025 at 11:46AM ET.
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Kansas City at Jacksonville

October 6, 2025
img8:15 PM Eastern

Kansas City started this season 0-2, but they have righted the ship and have won their past two games including 37-20 over the Ravens last week. Patrick Mahomes threw for 270 yards and Xavier Worthy returned from a shoulder injury to catch five passes for 83 yards. The Chiefs have won the past eight meetings with Jacksonville dating to 2010. The last one was a 17-9 victory in 2023. Kansas City has won 13 of 17 road games and 17 of 20 overall against AFC opponents. The Jaguars have lost 13 of 18 against the AFC. Trevor Lawrence has been adequate this season, but not great with five TD passes and four interceptions for a 48.3 QB rating. The Jaguars come off a 26-21 win over San Francisco by scoring 17 points off turnovers while getting an 87-yard punt return for a TD from Parker Washington. They likely won't be so fortunate against the Chiefs. Jacksonville is 1-6 ATS its past seven Monday games and 4-0 UNDER after allowing more than 250 yards passing its previous game. The Jaguars are 5-1 UNDER their past six home games and 6-1 UNDER versus the AFC West. Kansas City is 7-2 UNDER against the AFC South and it has gone UNDER six of seven October games. KC has the motivation here because 3-2 is a lot different than 2-3. Take the Chiefs and the UNDER.

1 unit on Kansas City -3.5 (-103) (risk 1 to return 1.97)
Result:
LOSS
1 unit on Game Total UNDER 45.5 -105 (risk 1 to return 1.95)
Result:
LOSS
Final
1
2
3
4
F
Kansas City Chiefs
7
7
0
14
28
Jacksonville Jaguars img
0
7
14
10
31
consensus consensus
odds odds
 
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