Kansas City at Arizona

Andy Reid doesn't have a history of being too excited about winning in the preseason. Still, there could be some motivation for the Chiefs to quickly atone for their embarrassing performance in the Super Bowl against the Eagles. Jonathan Gannon is 2-4 straight up and ATS in preseason with Arizona, and the Cardinals lost all three in 2024, and two went UNDER. The Cardinals have gone UNDER four of six preseason games, and they averaged only 13.0 points per game in 2024. The Chiefs' backup quarterbacks behind Patrick Mahomes are Gardner Minshew, Bailey Zappe, and Chris Oladokun. Minshew has plenty of NFL experience, and Zappe has appeared in 15 games in his three seasons. Oladokun was drafted in 2022 but has appeared in just one regular-season game. Arizona will have Jacoby Brissett and Clayton Tune backing up Kyler Murray, who is expected to start in this game along with some other starters, although likely for just a couple of series. Arizona has gone UNDER four of five preseason Game One games. Take the Chiefs on the moneyline and the UNDER.