Indianapolis at Los Angeles

Indianapolis soared OVER the total by 12 points in its 31-27 win over Arizona. Daniel Jones threw two TD passes and rushed for a score, and Jonathan Taylor rushed for 123 yards. The Colts are averaging 32.3 points this season. They have gone OVER six of nine dating to last season and five of their past six road games. Indianapolis is 8-2 OVER against AFC opponents and 6-1 OVER following an ATS loss. Also, the Colts are 6-1 OVER after allowing fewer than 90 yards rushing in their previous game, and they are 11-1 OVER coming off a non-conference home win. The Chargers have gone OVER six of eight home games and 10 of 12 against the AFC South. They scored their most points this season while defeating Miami 29-27, and it went OVER by 13 points last week. Los Angeles totaled 403 yards of offense, and Justin Herbert threw for 264 yards and two TDs. Take the OVER.