Houston at Jacksonville

Winless Houston has been in both games, losing 14-9 to the Rams and 20-19 to Tampa Bay. They lost to the Bucs last week on a touchdown with six seconds left. The defense is seventh in the NFL in points allowed, while QB C.J. Stroud is excellent, with 44 TDs and 18 picks in his young career. The Texans are on a 5-3-1 ATS run on the road. Rebuilding Jacksonville comes off a 31-27 loss to Cincinnati. QB Trevor Lawrence has thrown three interceptions in two games. Houston swept the series against the Jaguars last year and is 3-1 SU/ATS in the previous four meetings, including a 37-17 win on this field as a +7.5 underdog. Play Houston.