This pick was released to clients on November 20, 2025 at 10:41AM ET.
img NFL

Buffalo at Houston

November 20, 2025
img8:15 PM Eastern

Buffalo exploded for 44 points with Josh Allen scoring six TDs against Tampa Bay, but it will be a different story on Thursday night when the Bills face the NFL's #1 defense. Houston allows just 258.1 total yards and 16.3 points per game, and the Texans are #3 in pass defense, right behind the #2 Bills. The Texans stayed UNDER by eight points even with a low posted total of 37 when they beat Tennessee 16-13 on Sunday. The Titans were held to 229 total yards, 58 on the ground. Buffalo has gone UNDER in four of six games, and seven of the past eight meetings have stayed UNDER. Houston is on an 8-3 UNDER run, including four of five home games. The Bills are 4-0 UNDER after allowing more than 350 total yards in their previous game, and the Texans are 14-2-2 UNDER after an ATS loss. Take the UNDER. 

1 unit on Game Total UNDER 43.5 -107 (risk 1 to return 1.93)
Result:
WIN
Final
1
2
3
4
F
Buffalo Bills
6
10
0
3
19
Houston Texans img
3
17
3
0
23
consensus consensus
odds odds
 
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