Previous Matchups & Picks

September 13, 2026 1:00pm ET
@
Buffalo Bills
Buffalo Bills
#463
Houston Texans
Houston Texans
#464

Lines & Odds

-1 (-110)
ATS
+1 (-110)
-115
Moneyline
-103
OVER 44.5 (-110)
Total
UNDER 44.5 (-110)

Bills vs. Texans Spread Picks

Get this week's Bills vs. Texans point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Bills vs. Texans.

Public Consensus

Who was the public on? 55% of the public bets were on Buffalo Bills on the -1 ATS. 73% of the public money was on Buffalo Bills to win on the moneyline. And, 83% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Buffalo would win by a score of 22.2 to 21.9 with Buffalo winning on the moneyline, Houston winning on the spread and the game going UNDER the total.

Pro Picks

This Pro Pick was released to clients on September 11, 2026 at 12:22PM ET.
img NFL

Buffalo at Houston

September 13, 2026
img1:00 PM Eastern

Houston brings the defense that made a real case as the league's best unit a year ago, and Buffalo counters with a version of itself that looks different at the top. Joe Brady was promoted from offensive coordinator to head coach after Sean McDermott was let go, so Josh Allen keeps the same play-caller, but Brady is running his first game as a head coach and everything that comes with it: clock management, fourth-down calls, in-game adjustments a rookie head coach has never had to make. That kind of transition tends to slow a team down in a season opener even when the scheme itself hasn't changed. Houston's own offense is now in its second year under coordinator Nick Caley, which points to a more measured script early rather than a shootout. Two strong defenses, with one sideline learning on the job in real time, are the recipe for a total that stays under. Take the UNDER.

Final Score

1
2
3
4
F
Buffalo Bills img
3
21
3
9
36
Houston Texans
7
14
0
10
31

NFL Pro Pick Results

Here’s how my Pro Picks are performing.

NFLNFL All Picks last 25.1 years
Wins
Losses
Units
3,235
2,885
+175.20
NFLNFL Max Plays last 25.1 years
Wins
Losses
Units
1,323
1,131
+148.67
NFLNFL Free Picks last 16.8 years
Wins
Losses
Units
263
176
+97.72
NFLNFL All Preseason Picks last 24.0 years
Wins
Losses
Units
499
429
+46.95
NFLNFL All Playoff Picks last 13.1 years
Wins
Losses
Units
227
177
+42.81
NFLNFL Max Plays this season last 8 days
Wins
Losses
Units
1
0
+1.74
November 20, 2025 8:15pm ET
@
Buffalo Bills
Buffalo Bills
#111
Houston Texans
Houston Texans
#112

Lines & Odds

-4.5 (-110)
ATS
+4.5 (-110)
-243
Moneyline
+201
OVER 44.5 (-110)
Total
UNDER 44.5 (-110)

Public Consensus

Who was the public on? 60% of the public bets were on Buffalo Bills on the -4.5 ATS. And, 55% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Buffalo would win by a score of 23.2 to 20.8 with Buffalo winning on the moneyline, Houston winning on the spread and the game going UNDER the total.

Pro Picks

This Pro Pick was released to clients on November 20, 2025 at 10:41AM ET.
img NFL

Buffalo at Houston

November 20, 2025
img8:15 PM Eastern

Buffalo exploded for 44 points with Josh Allen scoring six TDs against Tampa Bay, but it will be a different story on Thursday night when the Bills face the NFL's #1 defense. Houston allows just 258.1 total yards and 16.3 points per game, and the Texans are #3 in pass defense, right behind the #2 Bills. The Texans stayed UNDER by eight points even with a low posted total of 37 when they beat Tennessee 16-13 on Sunday. The Titans were held to 229 total yards, 58 on the ground. Buffalo has gone UNDER in four of six games, and seven of the past eight meetings have stayed UNDER. Houston is on an 8-3 UNDER run, including four of five home games. The Bills are 4-0 UNDER after allowing more than 350 total yards in their previous game, and the Texans are 14-2-2 UNDER after an ATS loss. Take the UNDER. 

Final Score

1
2
3
4
F
Buffalo Bills
6
10
0
3
19
Houston Texans img
3
17
3
0
23
October 6, 2024 1:00pm ET
@
Buffalo Bills
Buffalo Bills
#457
Houston Texans
Houston Texans
#458

Lines & Odds

+1 (-105)
ATS
-1 (-115)
+104
Moneyline
-124
OVER 48 (-110)
Total
UNDER 48 (-110)

Public Consensus

Who was the public on? 58% of the public bets were on Buffalo Bills on the +1 ATS. And, 64% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Buffalo would win by a score of 25.1 to 23.2 with Buffalo winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Buffalo Bills
3
0
14
3
20
Houston Texans img
14
3
3
3
23
October 3, 2021 1:00pm ET
@
Houston Texans
Houston Texans
#267
Buffalo Bills
Buffalo Bills
#268

Lines & Odds

+18.5 (-110)
ATS
-18.5 (-110)
+1003
Moneyline
-1622
OVER 47.5 (-110)
Total
UNDER 47.5 (-110)

Public Consensus

Who was the public on? 51% of the public bets were on Buffalo Bills on the -18.5 ATS. And, 63% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Buffalo would win by a score of 31.7 to 17.8 with Buffalo winning on the moneyline, Houston winning on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on September 29, 2023 at 11:34AM ET.
img NFL

Houston at Buffalo

October 3, 2021
img1:00 PM Eastern

The Buffalo Bills have scored 78 points in their last two games, and they certainly could be heading for more of the same as Houston will be led once again by Davis Mills. Houston may have some time-of-possession issues in this game, and that affords the Buffalo offense a lot of opportunities. Where I think this total gets threatened is in the 4th quarter when the Houston offense is most likely going to be facing a lot of second and third-team players. It looks to me that if the Texans can get to 13 points, it very well could put this one OVER the total. Josh Allen has seen 13 of his last 20 games play OVER the total, and the Bills games averaged 53.1 points per game last season. Make the play on the OVER.

Final Score

1
2
3
4
F
Houston Texans
0
0
0
0
0
Buffalo Bills img
7
9
3
21
40
January 4, 2020 4:35pm ET
@
Buffalo Bills
Buffalo Bills
#141
Houston Texans
Houston Texans
#142

Lines & Odds

+2.5 (-110)
ATS
-2.5 (-120)
+117
Moneyline
-134
OVER 43 (-110)
Total
UNDER 43 (-110)

Public Consensus

Who was the public on? 55% of the public bets were on Buffalo Bills on the +2.5 ATS. And, 62% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Houston would win by a score of 22.9 to 21.1 with Houston winning on the moneyline, Buffalo winning on the spread and the game going OVER the total.

Pro Picks

These Pro Picks were released to clients on January 12, 2024 at 10:18AM ET.
img NFL

Buffalo at Houston

January 4, 2020
img4:35 PM Eastern

The Bills made their own bye last week, resting players against the Jets. RB Devin Singletary (775 yards, 5.1 ypc) leads the No. 5 ranked ground attack, which should chew up yards and the clock along with mobile QB Josh Allen (20 TDs, 9 INTS), who made big strides. The Bill's punishing defense is why they're here as the "D" is third in yards allowed, #10 against the run, fourth versus the pass, and second in points (16.2 per game). On the road this season, they were actually better, allowing just 15.6 points. Buffalo's offense scored just 19.6 points per game and struggles down the stretch, averaging just 13.3 per game in their last four contests. Buffalo is 19-7 UNDER the total on the road, 19-7 UNDER as a dog, and 35-16 UNDER as a road dog. Houston's defense isn't in the same league, ranked #18 in points surrendered, #24 against the run (120 ypg), fourth-worst against the pass. Over the last seven seasons, teams like Houston that are coming off a blowout loss by 20 points or more to the hand of a division rival are 59-29 to the UNDER. Teams off a double digit loss are 368-290 to the UNDER over the last eight seasons when the total falls between 41.5 - 50. Combined this season, these teams were 21-11 to the UNDER. The Bills were 6-2 on the road this season, good for a better win percentage than Houston had at home. Teams off a home blowout loss of more than 14 points are just 277-546 (33.7%) straight-up in their next game. That includes a mark of just 199-494 (28.7%) if not favored by at least a field goal. Under Sean McDermott, the Bills are 13-8 straight-up off a loss. Also, this game opened to a total of 41 and has been bet up by the public to 44. I think the oddsmakers had it right to start. Play Buffalo to win this one straight-up and also play the UNDER in this game.

Final Score

1
2
3
4
O
F
Buffalo Bills
7
6
3
3
0
19
Houston Texans img
0
0
8
11
3
22

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