USC at Colorado

The hype machine that is Colorado started the season on fire at 3-0. They took to the road last week vs. Oregon and were completely humiliated in a 42-6 trainwreck. It won't get any easier vs. USC, and it seems like Coach Prime has a target on his back due to his own success. The injuries are mounting with Travis Hunter, a great WR and DB, remaining out, and Shilo Sanders was hospitalized this week after peeing blood after the game. USC has a Heisman-winning QB in Caleb Williams, and he has led an offense putting up 55 PPG. This Colorado defense may be without two DBs, who are also their best defenders to a defense that was shredded last week, and playing a team with an even better offense. I think this game will look like the Oregon one with a huge margin. Make the play on USC.