This pick was released to clients on October 16, 2025 at 10:38AM ET.
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Purdue at Northwestern

October 18, 2025
img3:00 PM Eastern

Purdue has lost four straight, including two tough games against Top 25 teams (Indiana and Illinois), as well as a game against USC. Sophomore QB Ryan Browne has averaged 265 yards passing in the last four games, including topping 300 yards twice. They led Minnesota last week, 20-13 in the third quarter, before losing, 27-20. Northwestern is in an emotional let-down spot after upsetting Penn State, 22-21, as a +20 underdog. QB Preston Stone (8 TDs, 6 INTs) leads a passing offense that is 120th in the country in yards (168.6 per game), while the defense ranks 124th on third down (47.54%). Play Purdue on the moneyline. 

1.5 units on Purdue +145 (moneyline) (risk 1.5 to return 3.68)
Result:
LOSS
Final
1
2
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4
F
Purdue Boilermakers
0
0
0
0
0
Northwestern Wildcats img
3
10
6
0
19
consensus consensus
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