It's not just the Governor's Cup that is on the line for Kentucky in this in-state rivalry match-up against Louisville. The 5-6 Wildcats need to win here to become Bowl eligible. That's a big deal for Kentucky. The Wildcats had put a late stretch hot streak to get into this position, beating Tennessee Tech, 42-10, upsetting Florida at home in smashing fashion, 38-7, and upsetting Auburn, 10-3, as an 11-point road underdog. But Kentucky's win streak was halted by Vanderbilt, 45-17, on the road last week. Now the Wildcats go from playing one of the better teams in the SEC to a middle-of-the-road ACC team. In other words, a step down. The Cardinals are in a late-season rut, losers of three in a row. They've scored only 51 combined points in these three games, all losses: SMU (38-6), Clemson (20-19), and California (29-26 in overtime), as an 18.5-point home favorite. The Cardinals are the more banged-up team, too, hit hard at the skill positions. Their top three running backs - Isaac Brown, Keyjuan Brown, and Duke Watson - are out, along with their top wide receiver, Chris Bell, who leads Louisville with 917 receiving yards and six touchdown catches. In addition, quarterback Miller Moss is questionable. Take Kentucky.
This pick was released to clients on November 27, 2025 at 10:33AM ET.
Kentucky at Louisville
November 29, 2025
1 unit on Kentucky +3 (-108) (risk 1 to return 1.93)
Result:
LOSS
LOSS
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