Jacksonville State destroyed Southern Miss 44-7 last year, but the Gamecocks are underdogs this week, even though both teams are 2-2, and the Golden Eagles come off a 30-20 loss to Louisiana Tech as a 3-point underdog, and it went UNDER. Jacksonville State defeated Murray State 45-10, and the Gamecocks are 5-0 ATS after winning by at least 20 points in their previous game and 5-1 ATS after allowing fewer than 20. Southern Miss is 2-8 ATS in non-conference games. Jacksonville State has gone UNDER five of its past seven games, and it has won 10 of 14 outright. The Golden Eagles have lost 12 of 14 overall and six of eight at home. They have lost 14 of 19 against C-USA teams. The Gamecocks totaled 531 yards against Murray State, including 329 on the ground. Gavin Wimsatt finished with 188 passing yards, and Cam Cook had 22 receptions for 147 yards, and the game still stayed UNDER. Take Jacksonville State on the moneyline and play the UNDER.
These picks were released to clients on September 25, 2025 at 12:13PM ET.
Jacksonville State at Southern Miss
September 27, 2025
1 unit on Jacksonville State +160 (moneyline) (risk 1 to return 2.6)
Result:
LOSS
LOSS
1 unit on Game Total UNDER 54.5 -108 (risk 1 to return 1.93)
Result:
LOSS
LOSS
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