This pick was released to clients on November 20, 2025 at 11:06AM ET.
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Duke at North Carolina

November 22, 2025
img3:30 PM Eastern

Duke has a terrific offense, averaging 420 yards and 32.1 points behind QB Darian Mensah (25 TDs, 4 INTs) and RB Nate Sheppard (700 yards, 6.3 ypc). They've averaged 34.7 points over the last seven contests, including a 46-45 win at Clemson as a dog. North Carolina has little offensive punch after a 28-12 loss to Wake Forest. The defense surrendered 223 rushing yards to Wake Forest. The ground game averages 3.7 yards per carry. The offense ranks 129th in total yards, while the defense is 93rd on third down (42.3%). North Carolina is on an 8-21-1 ATS run. Play Duke. 

1.5 units on Duke -6.5 (-109) (risk 1.5 to return 2.88)
Result:
WIN
FINAL
1
2
3
4
F
Duke Blue Devils img
7
10
7
8
32
North Carolina Tar Heels
7
3
8
7
25
consensus consensus
odds odds
 
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