Colorado is 2-4 and winless in Big 12 play, and its latest loss was 27-24 to No. 11 Utah. Three of its six games- a 14-13 win at Georgia Tech, a 23-13 loss at Baylor, and that Utah game–were decided by 10 points or fewer. The other two losses, 41-7 at Northwestern and 29-7 against No. 12 Texas Tech, were the lopsided ones. Colorado's leading passer threw for 290 and 256 yards in its last two games, both against ranked opponents. Oklahoma State is 4-2 and scores 37.2 points per game, a figure that includes a 59-0 win over Murray State. Against its five FBS opponents, the Cowboys have allowed 28.4 points per game: 24 at Tulsa, 31 to Oregon, 24 at West Virginia, 28 to UCF and 35 at Houston. Its three FBS wins came by 8, 17, and 14 points against Oregon, West Virginia, and UCF. Its two FBS losses were 24-10 at Tulsa and 35-32 at Houston last Saturday. Oklahoma State coach Eric Morris called Colorado the "best two-win team" in the country this week. I'm on Colorado against the spread Saturday night.
This Pro Pick was released to clients on October 22, 2026 at 1:27PM ET.
Colorado at Oklahoma State
October 24, 2026
0.5 unit on Colorado +13.5 (-101) (risk 0.5 to return 1)
Result:
LOSS
LOSS
TAKE THE GUESSWORK OUT OF SPORTS BETTING
Get free CFB Picks
I pore over the data, injuries, news, and odds every morning.
You get the best bets delivered to your inbox.