San Francisco 49ers at Detroit Lions
Computer Picks, Predictions & Odds

NFL Football Computer Pick with Spread, Moneyline & Total Odds

Below you will find San Francisco 49ers at Detroit Lions picks, predictions and odds along with a matchup preview.
Check out my computer picks and predictions in NFL Football on every game weekly.

Week 1: September 12, 2021 @ 1:00 PM ET

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Note: These are computer-derived picks and do NOT represent my official picks. In order to make final picks, there is much more analysis required (injuries, trends, situations and other technical analysis). If you want my full analysis, detailed write-ups, and official picks, be sure to get my email newsletter.


NFL Football Picks & Predictions Public Consensus

TEAM ATS TOTAL
BETS % BETS %
49ers 151 
82%
O 683 
49%
Lions 33 
18% 
U 725 
51% 

Wunderdog NFL Football Betting Picks & Predictions: Predicted Score

TEAM ODDS SCORE % CHANCE TO WIN
49ers -429 27.075
73%
Lions +347 20.425
27%

Wunderdog NFL Football Computer Predictions Against The Spread and Total

TEAM ATS TOTAL
49ers -9.5 46.0 O
Lions +9.5 46.0
FINAL SCORE
TEAM 1Q 2Q 3Q 4Q FINAL
49ers 7 24 7 3 41
Lions 0 10 7 16 33

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