Indianapolis Colts at Buffalo Bills
Picks, Predictions & Odds

NFL Football Computer Pick with Spread, Moneyline & Total Odds

Below you will find Indianapolis Colts at Buffalo Bills picks, predictions and odds along with a matchup preview.
Check out my computer picks and predictions in NFL Football on every game weekly.

Week 11: November 21, 2021 @ 1:00 PM ET

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Note: These are computer-derived picks and do NOT represent my official picks. In order to make final picks, there is much more analysis required (injuries, trends, situations and other technical analysis). If you want my full analysis, detailed write-ups, and official picks, be sure to get my email newsletter.


NFL Football Picks & Predictions Public Consensus

TEAM ATS TOTAL
BETS % BETS %
Colts 1063 
57%
O 562 
48%
Bills 791 
43% 
U 603 
52% 

Wunderdog NFL Football Betting Picks & Predictions: Predicted Score

TEAM ODDS SCORE % CHANCE TO WIN
Colts +255 21.134
26%
Bills -307 28.066
74%

Wunderdog NFL Football Computer Predictions Against The Spread and Total

TEAM ATS TOTAL
Colts +7.0 49.5
Bills -7.0 49.5 U
FINAL SCORE
TEAM 1Q 2Q 3Q 4Q FINAL
Colts 14 10 14 3 41
Bills 0 7 0 8 15

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