Previous Matchups & Picks

December 28, 2025 1:00pm ET
@
Jacksonville Jaguars
Jacksonville Jaguars
#423
Indianapolis Colts
Indianapolis Colts
#424

Lines & Odds

-4 (-110)
ATS
+4 (-110)
-212
Moneyline
+178
OVER 48.5 (-110)
Total
UNDER 48.5 (-110)

Jaguars vs. Colts Spread Picks

Get this week's Jaguars vs. Colts point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Jaguars vs. Colts.

Public Consensus

Who was the public on? 62% of the public bets were on Jacksonville Jaguars on the -4 ATS. And, 60% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Jacksonville would win by a score of 26.0 to 23.5 with Jacksonville winning on the moneyline, Indianapolis winning on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on December 26, 2025 at 10:12AM ET.
img NFL

Jacksonville at Indianapolis

December 28, 2025
img1:00 PM Eastern

Jacksonville has won six in a row behind QB Trevor Lawrence (26 TDs, 11 INTs), averaging 34.1 points. They come off a 34-20 win at Denver, one of the best defensive teams in the league. The Jaguars are on an 8-4 run OVER the total, including 6-1 OVER on the road. Indianapolis plays its second straight at home, after a 48-27 loss to San Francisco. New QB Philip Rivers threw for 277 yards and two touchdowns. The defense is 25th in yards allowed, with the Colts on a 5-2 run OVER the total at home. Take Jacksonville/Indianapolis OVER the total.

Final Score

1
2
3
4
F
Jacksonville Jaguars img
0
7
10
6
23
Indianapolis Colts
3
7
7
0
17

NFL Pro Pick Results

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December 7, 2025 1:00pm ET
@
Indianapolis Colts
Indianapolis Colts
#131
Jacksonville Jaguars
Jacksonville Jaguars
#132

Lines & Odds

-1.5 (-110)
ATS
+1.5 (-110)
-126
Moneyline
+107
OVER 45 (-110)
Total
UNDER 45 (-110)

Public Consensus

Who was the public on? 55% of the public bets were on Jacksonville Jaguars on the +1.5 ATS. And, 55% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Indianapolis would win by a score of 24.5 to 24.4 with Indianapolis winning on the moneyline, Jacksonville winning on the spread and the game going OVER the total.

Pro Picks

These Pro Picks were released to clients on December 05, 2025 at 12:33PM ET.
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Indianapolis at Jacksonville

December 7, 2025
img1:00 PM Eastern

It's a battle for first place in the AFC South, and Indianapolis will look to bounce back from three close losses in its past four games, including 20-16 to Houston on Sunday, when the Colts were held to fewer than 20 points for the first time this season. Daniel Jones was 14 of 27 passing for 201 yards and two TDs while playing through a lower leg injury, although he says it is improving each week. The Colts' defense has been overlooked as they allow 20.8 points per game. Indianapolis is 7-2 ATS in its past seven games against AFC opponents. Jacksonville is on a three-game win streak, but the last two were against Arizona and Tennessee, who combined for a 4-20 record. The Jaguars have gone UNDER six of their past seven home games, and they are 7-1 UNDER their past eight December games. Curiously, Indianapolis is still the slight favorite on the road even after its recent losses, which suggests the oddsmakers see this matchup differently. Take the Colts and the UNDER.

Final Score

1
2
3
4
F
Indianapolis Colts
7
3
3
6
19
Jacksonville Jaguars img
14
14
0
8
36
January 5, 2025 1:00pm ET
@
Jacksonville Jaguars
Jacksonville Jaguars
#349
Indianapolis Colts
Indianapolis Colts
#350

Lines & Odds

+3.5 (-110)
ATS
-3.5 (-110)
+161
Moneyline
-190
OVER 46 (-110)
Total
UNDER 46 (-110)

Public Consensus

Who was the public on? 66% of the public bets were on Indianapolis Colts on the -3.5 ATS. And, 58% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Indianapolis would win by a score of 25.7 to 19.7 with Indianapolis winning on the moneyline and on the spread and the game going UNDER the total.

Pro Picks

This Pro Pick was released to clients on January 03, 2025 at 10:18AM ET.
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Jacksonville at Indianapolis

January 5, 2025
img1:00 PM Eastern

Indianapolis has been eliminated from playoff contention, having lost six of its past nine games, including a shocking 45-33 defeat at the hands of the hapless New York Giants last week. It ended a 10-game skid for New York, who got 309 passing yards and four TDs from Drew Lock. The Colts are 1-5 ATS after totaling more than 350 yards in their previous game and 1-5 ATS as favorites of 3.5-10.0 points. Indianapolis is 0-5 ATS in its past five January games. Jacksonville has won five of six meetings, including 37-34 on Oct. 6. The Jaguars have lost many close games this season, but they did pull off a 20-13 victory over Tennessee on Sunday. Mac Jones finished 15 of 22 for 174 yards and two TDs with no picks. Jacksonville is 8-2 ATS in its past 10 meetings with the Colts, who are disappointed after missing the postseason, while the Jags would like to end on a winning note, and they're getting points. Take the Jaguars.

Final Score

1
2
3
4
O
F
Jacksonville Jaguars
7
6
0
10
0
23
Indianapolis Colts img
7
13
0
3
3
26
October 6, 2024 1:00pm ET
@
Indianapolis Colts
Indianapolis Colts
#459
Jacksonville Jaguars
Jacksonville Jaguars
#460

Lines & Odds

+3.5 (-105)
ATS
-3.5 (-118)
+175
Moneyline
-207
OVER 44.5 (-110)
Total
UNDER 44.5 (-110)

Public Consensus

Who was the public on? 52% of the public bets were on Jacksonville Jaguars on the -3.5 ATS. And, 57% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Jacksonville would win by a score of 23.6 to 22.4 with Jacksonville winning on the moneyline, Indianapolis winning on the spread and the game going OVER the total.

Pro Picks

These Pro Picks were released to clients on October 04, 2024 at 9:46AM ET.
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Indianapolis at Jacksonville

October 6, 2024
img1:00 PM Eastern

Jacksonville is searching for its first win and it likely won't get it this week against Indianapolis, which is coming off two impressive wins over Chicago and Pittsburgh after losing close games in its first two games. Joe Flacco did an imitation of what he did last year with Cleveland as he relieved injured starter Anthony Richardson and tossed two TD passes and the Colts beat the Steelers 27-24. Michael Pittman Jr. had six catches for 113 yards for the Colts, who are 17-4 ATS their past 21 games in Week 5. The Jaguars are 2-10 ATS in Week 5 and 1-6 ATS and 7-0 UNDER their past seven games as home favorites of 0.5-3.0 points. Jacksonville is 10-1 UNDER as a favorite overall  of 0.5-3.0 points. The Jaguars lost 24-20 to Houston even though the Texans had 12 penalties called against them. Jacksonville led for most of the second half before succumbing to another loss and its third UNDER in four games. Indianapolis is in double revenge after losing both meetings last season and the Jaguars have lost eight straight against AFC opponents. Take the Colts and the UNDER.

Final Score

1
2
3
4
F
Indianapolis Colts
7
3
0
24
34
Jacksonville Jaguars img
0
13
7
17
37
October 15, 2023 1:00pm ET
@
Indianapolis Colts
Indianapolis Colts
#263
Jacksonville Jaguars
Jacksonville Jaguars
#264

Lines & Odds

+4 (-110)
ATS
-4 (-110)
+172
Moneyline
-205
OVER 44 (-110)
Total
UNDER 44 (-110)

Public Consensus

Who was the public on? 55% of the public bets were on Jacksonville Jaguars on the -4 ATS. And, 52% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Jacksonville would win by a score of 26.7 to 19.0 with Jacksonville winning on the moneyline and on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on October 13, 2023 at 11:32AM ET.
img NFL

Indianapolis at Jacksonville

October 15, 2023
img1:00 PM Eastern

Jacksonville is getting progress from QB Trevor Lawrence, but he still has a long way to go. What he has done is cut down on his turnovers. Last year Lawrence threw 13 INTs and so far this year only two. The Jags are still not scoring a lot by the air as Lawrence has just five TD passes on the season. What all these numbers have led to is Jacksonville playing under in 25 of Lawrence's first 41 NFL starts. Indianapolis might be content to run the ball as they have generated 125 or more rushing yards in each of their last four games. This should be a tight game and whoever wins the ground war is going to emerge a healthy 4-2 from this game. I like the UNDER.

Final Score

1
2
3
4
F
Indianapolis Colts
3
3
0
14
20
Jacksonville Jaguars img
0
21
10
6
37

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