Denver Broncos vs Indianapolis Colts Point Spread Picks

Broncos vs. Colts Spread Picks

Get this week's Broncos vs. Colts point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Broncos vs. Colts.

Public Consensus

Who was the public on? 56% of the public bets were on Denver Broncos on the -1 ATS. And, 56% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Indianapolis would win by a score of 22.9 to 19.9 with Indianapolis winning on the moneyline and on the spread and the game going UNDER the total.

Pro Picks

This Pro Pick was released to clients on September 12, 2025 at 9:49AM ET.

NFL

Denver at Indianapolis

September 14, 2025

4:05 PM Eastern

Denver shut down Tennessee in the opener at home, 20-12. Now they head out for their first road game. The offense turned it over four times. Denver was 6-2 at home last season, but had a losing road record. In 2023, they also had a winning home record but a losing road mark. The Broncos are on a 1-4 ATS run, including 0-3 ATS on the road. Indianapolis plays its second straight at home after crushing the Dolphins, 33-8. QB Daniel Jones threw for 272 yards while the ground attack had 156 yards. The defense allowed 211 total yards under new coordinator Lou Anarumo. The Colts are on a 6-3 ATS run at home. Play Indianapolis. 

Final Score

1

2

3

4

F

Denver Broncos

7

14

7

0

28

Indianapolis Colts

6

14

3

6

29

Public Consensus

Who was the public on? 69% of the public bets were on Denver Broncos on the -4.5 ATS. And, 51% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Denver would win by a score of 25.4 to 18.2 with Denver winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1

2

3

4

F

Indianapolis Colts

7

6

0

0

13

Denver Broncos

0

7

3

21

31

Computer Predictions

My computer prediction for this game was that Indianapolis would win by a score of 19.5 to 18.5 with Indianapolis winning on the moneyline, Denver winning on the spread and the game going UNDER the total.

Pro Picks

This Pro Pick was released to clients on August 07, 2024 at 3:26PM ET.

NFL

Denver at Indianapolis

August 11, 2024

1:00 PM Eastern

Denver has a terrific head coach in Sean Payton. That's a big advantage in preseason with so many players to examine and teach. He has a good August QB rotation, building around Bo Nix teamed with veterans Jarrett Stidham and Zach Wilson. In Payton's last preseason game, Denver shut out Los Angeles, 41-0, as Stidham threw for 236 yards. Indianapolis didn't change much this offseason. Last year's offense was 25th in total yards and 29th in points. QB Anthony Richardson is back after playing in just four games as a rookie before shoulder surgery, with the backups 39-year-old Joe Flacco (13 TDs, 8 INTs in 2023) and Sam Ehlinger (career 3 TDs, 3 picks). The defensive secondary is below-average and inconsistent while allowing too many big plays. Play Denver.

Final Score

1

2

3

4

F

Denver Broncos

0

13

14

7

34

Indianapolis Colts

3

7

7

13

30

Public Consensus

Who was the public on? 56% of the public bets were on Denver Broncos on the -3 ATS. And, 61% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Denver would win by a score of 21.3 to 19.5 with Denver winning on the moneyline, Indianapolis winning on the spread and the game going UNDER the total.

Final Score

1

2

3

4

O

F

Indianapolis Colts

0

3

3

3

3

12

Denver Broncos

3

3

3

0

0

9

Public Consensus

Who was the public on? 71% of the public bets were on Indianapolis Colts on the -6 ATS. And, 51% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Indianapolis would win by a score of 24.1 to 17.6 with Indianapolis winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1

2

3

4

F

Denver Broncos

0

6

7

0

13

Indianapolis Colts

0

3

9

3

15