Previous Matchups & Picks

December 28, 2025 8:20pm ET
@
Chicago Bears
Chicago Bears
#429
San Francisco 49ers
San Francisco 49ers
#430

Lines & Odds

+3.5 (-105)
ATS
-3.5 (-115)
+175
Moneyline
-208
OVER 51.5 (-110)
Total
UNDER 51.5 (-110)

Bears vs. 49ers Spread Picks

Get this week's Bears vs. 49ers point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Bears vs. 49ers.

Public Consensus

Who was the public on? 64% of the public bets were on San Francisco 49ers on the -3.5 ATS. And, 50% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that San Francisco would win by a score of 26.4 to 25.4 with San Francisco winning on the moneyline, Chicago winning on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on December 26, 2025 at 10:12AM ET.
img NFL

Chicago at San Francisco

December 28, 2025
img8:20 PM Eastern

Malign the Bears at your own peril. All Chicago has done is go 11-4, which is the second-best record in the NFC, and tie with Jacksonville for the second-best ATS mark at 10-4-1. Chicago has won seven of its last eight games, with three of their past four victories coming against teams currently in the playoffs — the Steelers, Eagles, and Packers. First-year Bears head coach Ben Johnson is doing a great job bringing along potential franchise QB Caleb Williams. The Bears are the No. 2 rushing team in the NFL. That has taken some of the pressure off Williams, too. San Francisco's defense is down because of injuries to its two best defenders, linebacker Fred Warner and defensive end Nick Bosa. The 49ers just allowed 44-year-old Philip Rivers and the Colts to score 27 points and gain 312 yards this past Monday night. San Francisco's offense has been clicking. The Bears, however, are the most opportunistic team in the NFL with a league-best 31 takeaways and a plus-21 ratio. Chicago also has a rest advantage, having last played on Saturday, while the 49ers are on a short week following their Monday victory. Take the Bears.

Final Score

1
2
3
4
F
Chicago Bears
14
7
7
10
38
San Francisco 49ers img
14
14
7
7
42

NFL Pro Pick Results

Here’s how my Pro Picks are performing.

NFLNFL All Picks last 25.0 years
Wins
Losses
Units
3,208
2,857
+182.36
NFLNFL Max Plays last 25.0 years
Wins
Losses
Units
1,320
1,125
+155.43
NFLNFL Free Picks last 16.6 years
Wins
Losses
Units
261
173
+99.53
NFLNFL All Preseason Picks last 24.0 years
Wins
Losses
Units
499
429
+46.95
NFLNFL All Playoff Picks last 13.1 years
Wins
Losses
Units
227
177
+42.81
NFLNFL Between teams last 4.2 years
Wins
Losses
Units
3
1
+1.80
December 8, 2024 4:25pm ET
@
Chicago Bears
Chicago Bears
#139
San Francisco 49ers
San Francisco 49ers
#140

Lines & Odds

+3 (-110)
ATS
-3 (-110)
+139
Moneyline
-163
OVER 43.5 (-110)
Total
UNDER 43.5 (-110)

Public Consensus

Who was the public on? 52% of the public bets were on San Francisco 49ers on the -3 ATS. And, 57% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that San Francisco would win by a score of 24.5 to 19.5 with San Francisco winning on the moneyline and on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on December 05, 2024 at 11:34AM ET.
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Chicago at San Francisco

December 8, 2024
img4:25 PM Eastern

Chicago has talent on offense and has gotten decent play out of rookie QB Caleb Williams (14 TDs, 5 INTs). But the defense has let them down, ranked 22nd in yards allowed and 25th against the run. They've lost six in a row, allowing an average of 23.1 points. San Francisco's defense is 24th in points surrendered (24.6 per game), 26th on third down (44.16%), and 31st in the red zone (70.73%). They haven't even shown up in the last two games, allowing 38 and 35 points. Take Chicago/San Francisco OVER the total. 

Final Score

1
2
3
4
F
Chicago Bears
0
0
6
7
13
San Francisco 49ers img
14
10
0
14
38
September 11, 2022 1:00pm ET
@
San Francisco 49ers
San Francisco 49ers
#463
Chicago Bears
Chicago Bears
#464

Lines & Odds

-6.5 (-110)
ATS
+6.5 (-110)
-278
Moneyline
+229
OVER 38 (-110)
Total
UNDER 38 (-110)

Public Consensus

Who was the public on? 54% of the public bets were on San Francisco 49ers on the -6.5 ATS. And, 59% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that San Francisco would win by a score of 24.6 to 17.9 with San Francisco winning on the moneyline and on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on September 08, 2023 at 1:08PM ET.
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San Francisco at Chicago

September 11, 2022
img1:00 PM Eastern

The Chicago Bears are not high on many lists regarding 2022 expectations. The Bears did not show much in terms of a home-field advantage last season finishing their home schedule at just 3-5. That gives a look to this game as a San Francisco easy win, but despite the 3-5 overall home record a year ago the Bears were out-scored at home by just 0.5ppg. That tells me this game will be a lot more competitive than it looks, and laying a TD on the road in week 1 is not a desirable position to be backing. Week 1 home dogs of 7 or more have covered 58.3% of all games. San Francisco went the last 6 games a year ago without scoring more than 27 points in any of them. The defense had to step up and win games. This was a team that went 8-4 on the road last year however 6 of those wins were by 1 score, and 5 were by 6 or fewer points. The Bears are getting no love but the line here is inflated for a week one road favorite. Make the play on Chicago.

Final Score

1
2
3
4
F
San Francisco 49ers
0
7
3
0
10
Chicago Bears img
0
0
7
12
19
October 31, 2021 1:00pm ET
@
San Francisco 49ers
San Francisco 49ers
#265
Chicago Bears
Chicago Bears
#266

Lines & Odds

-4.5 (-110)
ATS
+4.5 (-110)
-211
Moneyline
+180
OVER 40 (-110)
Total
UNDER 40 (-110)

Public Consensus

Who was the public on? 52% of the public bets were on Chicago Bears on the +4.5 ATS. And, 55% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that San Francisco would win by a score of 21.9 to 18.6 with San Francisco winning on the moneyline, Chicago winning on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on October 27, 2023 at 10:59AM ET.
img NFL

San Francisco at Chicago

October 31, 2021
img1:00 PM Eastern

This is about as low of an NFL total as you'll find without a blizzard roaring through. It's forecasted to be 55 degrees and sunny in Chicago on Sunday. San Francisco has lost four in a row with defensive problems. They're surrendering an average of 26.25 points during the skid. The 49ers have dropped to #20 in the NFL in points allowed and are 21-11 OVER the total as a favorite. Chicago's defense has also had problems giving up 24 and 38 points the last two games. They had four players on the COVID list for last week's game, including LB Caleb Johnson and star linebacker Robert Quinn. The Bears are #14 in points surrendered and #18 on third down. Also, the 49ers are 36-20 OVER the total against offenses that average 285 or fewer total yards per contest. Play this one to go OVER the total.

Final Score

1
2
3
4
F
San Francisco 49ers img
3
6
6
18
33
Chicago Bears
3
10
3
6
22
December 23, 2018 4:05pm ET
@
Chicago Bears
Chicago Bears
#125
San Francisco 49ers
San Francisco 49ers
#126

Lines & Odds

-4 (-115)
ATS
+4 (-120)
-200
Moneyline
+170
OVER 44 (-105)
Total
UNDER 44 (-115)

Public Consensus

Who was the public on? 61% of the public bets were on Chicago Bears on the -4 ATS. 62% of the public money was on Chicago Bears to win on the moneyline. And, 52% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Chicago would win by a score of 24.0 to 19.3 with Chicago winning on the moneyline and on the spread and the game going UNDER the total.

Pro Picks

This Pro Pick was released to clients on December 22, 2023 at 12:51PM ET.
img NFL

Chicago at San Francisco

December 23, 2018
img4:05 PM Eastern

The Chicago Bears just clinched the NFC North with a home win over the rival Packers, 24-17. There was plenty of celebrating as they haven't been to the playoffs since 2010. After clinching the title, now they fly to the West Coast. Chicago has injuries in the secondary, losing key slot corner Bryce Callahan (broken foot) and they are without Eddie Jackson (ankle injury). Chicago is a .500 team on the road, losing as a three-point favorite at the Giants, 30-27, squeezing by at Arizona (16-14) as -5.5 chalk, and losing at Miami as a TD-favorite, 31-28. NFL road teams that have covered five of six of the last seven games and have won 60% to 75% of their games are 45-82 ATS when facing a team with a losing record. San Francisco has a winning home record and is playing well, beating the Broncos (20-14) and Seahawks (26-23) the last two games. They were an underdog each time and this is their third straight home game. QB Nick Mullens (1,754 yards, 10 TDs, 6 picks) has been sharp along with star TE George Kittle (1,154 yards). Chicago is 23-42 ATS against teams averaging six yards per play or more, making this is a great situational spot for the home dog. Take San Francisco.

Final Score

1
2
3
4
F
Chicago Bears img
0
7
7
0
14
San Francisco 49ers
0
9
0
0
9

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