Milwaukee opens its first World Series since 1982 with the best record in baseball, 103-59, and the best run differential, plus 214. The Brewers scored the second-most runs in the majors, 832, and posted the second-best team ERA, 3.51. They are 55-26 at home. Jacob Misiorowski takes the ball with 11 days of rest. He led the majors with a 1.80 ERA, 252 strikeouts and a 0.80 WHIP over 174.2 innings, and he held hitters to a .157 average, the lowest for a full season on record. He did not finish the fifth inning in either of his first two postseason starts, which puts the bullpen with the second-best ERA in the league to work early. Nick Martinez is 36 and went 15-6 with a 3.10 ERA. Tampa Bay is 24-9 in games he starts, playoffs included, and his road ERA was better than that season figure. The Rays won 98 games, and there is an eight-win gap between that record and their run differential. Milwaukee is the team that earned its record on the scoreboard, and it gets a rested ace in Game 1. With the best run differential in baseball behind Misiorowski, I'm laying the runline with Milwaukee tonight.
This Pro Pick was released to clients on October 23, 2026 at 12:21PM ET.
Tampa Bay at Milwaukee
October 23, 2026
1 unit on Milwaukee -1.5 runs +138 (runline) (risk 1 to return 2.38)
Result:
LOSS
LOSS
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