The Pittsburgh Pirates are in a tough division. The Pirates are a decent 16-14, but in the NL Central, that is good for last place. If they were in the AL, that record would have them tied or ahead of two of the three divisions. The Cardinals are 16-13, which is good for third place. This series is a big one for Pittsburgh, and there's a notable difference between these teams. The Cards are three games over .500 but have a -9 run differential. The Pirates are two games over .500 with a +18 run differential. Take the more productive team with home-field advantage. Play Pittsburgh.
This Pro Pick was released to clients on April 29, 2026 at 11:36AM ET.
MLB
St. Louis at Pittsburgh
April 29, 2026
6:40 PM Eastern
1.5 units on Pittsburgh -120 (moneyline) (risk 1.5 to return 2.75)
Result:
LOSS
LOSS
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