This Pro Pick was released to clients on September 21, 2025 at 11:20AM ET.
img MLB

San Francisco at Los Angeles

September 21, 2025
img4:10 PM Eastern

Los Angeles is getting hot at the right time winning four in a row as it is poised to clinch the NL West. Shohei Ohtani hit his 53rd home run and the Dodgers came back from four runs down to beat the Giants 7-5 on Saturday night. San Francisco is all but out of the playoff race and the Giants have lost seven of eight road games and seven of eight overall. The Dodgers have won the past five meetings. They have won Emmet Sheehan's past seven starts with at least five days rest and his past six starts versus the NL West. Sheehan has yielded just three runs his past 18 2/3 innings. San Francisco will call on Trevor McDonald to make his first MLB start. He allowed two runs on three hits and a walk in two innings out of the bullpen on Tuesday. Take the Dodgers.

2 units on Los Angeles -208 (moneyline) (risk 2 to return 2.96)
Result:
LOSS
FINAL
1
2
3
4
5
6
7
8
9
R
San Francisco Giants img
0
0
0
0
0
0
0
3
0
3
Los Angeles Dodgers
0
0
0
0
0
0
1
0
0
1
consensus consensus
odds odds
 
TAKE THE GUESSWORK OUT OF SPORTS BETTING

Get free MLB Picks

I pore over the data, injuries, news, and odds every morning.
You get the best bets delivered to your inbox.