San Francisco starter Landen Roupp (3.24 ERA) has thrown well, with the Giants winning both of his road starts at Baltimore (6-3) and San Diego (3-2) as underdogs. He has an 18-to-5 strikeout-to-walk ratio in 16+ innings, while holding batters to a .219 average. Meanwhile, Cincinnati is on a 3-4 run, including losing 10-2 at home to the Angels as a -180 favorite. That game was the previous start made by Chase Burns, who has a 4.35 ERA at home. The offense is 27th in runs scored, 22nd in on-base percentage, and 26th in slugging. Play San Francisco.
This Pro Pick was released to clients on April 16, 2026 at 11:19AM ET.
San Francisco at Cincinnati
April 16, 2026
2 units on San Francisco +117 (moneyline) (risk 2 to return 4.34)
Result:
WIN
WIN
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