San Diego at Houston

Houston will turn to Zack Greinke to help cool off the red-hot Padres, whose hitters are batting only .159 against him in 117 at-bats. Fernando Tatis, Jr. is 3-for-8 versus Grienke, but Manny Machado and Eric Hosmer are a combined 10-for-44. The Astros have won six of his last seven starts, and his counterpart, Blake Snell, gave up five runs in 3 2/3 innings his last outing against Milwaukee. Snell has been knocked around for 16 runs in 16 1/3 innings on the road in his NL debut, and hitters are batting .280 against him on the road. Houston is 37-15 its past 52 home games versus left-handed starters and 7-3 its last 10 interleague home games against southpaw starters. Look for Houston to salvage the final game of the series. Play the Astros.