These Pro Picks were released to clients on October 01, 2025 at 11:21AM ET.
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San Diego at Chicago

October 1, 2025
img3:08 PM Eastern

Seiya Suzuki and Carson Kelly hit back-to-back homers to power Chicago past the Padres 3-1 on Tuesday. The Cubs will look to advance to the next round against Dylan Cease, who has a 4.55 ERA and a 1.33 WHIP this season. He is 1-9 with a 5.58 ERA on the road in 2025, and San Diego is 1-8 in Cease's past nine road starts against teams with winning records. The Padres are 1-6 in their past seven playoff road contests and 0-5 in Cease's past five Wednesday starts. Andrew Kittredge will start for the Cubs, with Shota Imanaga likely following in the second inning in a strategic move by manager Craig Counsell. The Cubs have gone OVER five of seven games, and they are 4-0-1 OVER against a starter with a WHIP greater than 1.30. Chicago is 4-0 OVER versus teams that scored two or fewer runs in their previous game. Take the Cubs to win, and bet the OVER.

1 unit on Chicago -109 (moneyline) (risk 1 to return 1.92)
Result:
LOSS
1 unit on Game Total OVER 6.5 -103 (risk 1 to return 1.97)
Result:
LOSS
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