Pittsburgh at St. Louis

St. Louis has certainly prevailed over the Pittsburgh Pirates as they took 14 of 19 last year and opened the 2020 season squeking by 5-4. Adam Wainwright has been troubled by this Pirates team where he owns just a 4.24 career ERA against them. Trevor Williams geets the ball for the Pirates, and he had success against them a year ago as he posted a 1.50 ERA in his two starts vs. the Cards. Home favorites tend to struggle in game 2 coming back as a home favorite again as the road team may take advantage of the letdown, and has held a +21.7% ROI. Make the play on Pittsburgh.