Los Angeles at Chicago

Los Angeles pitcher Yusei Kikuchi went 5-1 with a 2.70 ERA in his last 10 starts in 2024. In 2023, he went 11-6 with Toronto with a 3.86 ERA in 32 starts. He allowed one run in five innings in his last preseason start. Chicago was brutal last season, losing 121 games, including a 23-58 record at home. They're rebuilding after the offense was last in the majors in runs scored, and the pitching was 28th in ERA (4.68) allowing the most walks. Sean Burke started just three games last season but gets the opening day start after Chicago traded its best pitcher, Garrett Crochet, over the winter. The White Sox won 21.8% of their games in 2024 as an underdog of +125 or higher. Play Los Angeles.