Houston at Seattle

Seattle won five of the last six meetings against the Astros in 2025. The Mariners hope that trend continues as they try to snap a five-game skid, although Houston is on a four-game losing streak itself. The Astros are 1-5 on the road this season, and they have allowed 46 runs in their past six games. Their bullpen has been a disaster with a 7.09 ERA and a 1.73 WHIP. Tatsuya Imai has allowed four runs in 8 1/3 innings for the Astros. Emerson Hancock is coming off two great outings, allowing one run on six hits in 12 2/3 innings, including six hitless innings against Cleveland. Take the Mariners.