Houston at Colorado

Houston has won the past six meetings and covered the runline in five of them. The Astros have won seven of eight and 15 of 19 following their 6-5 victory on Tuesday night featuring Victor Caratini's grand slam. Colorado had a brief four-game win streak, but then reverted to its usual performance and lost nine of 11. The Rockies have lost 12 of their past 13 against American League teams and they have lost 13 of 15 overall at home. Hunter Brown is 8-3 with a 1.74 ERA and 118 strikeouts in 98 innings in 2025. The Astros have won his past six starts. Colorado has lost Austin Gomber's past four home starts and he has allowed 19 runs his past 21 2/3 innings. The Rockies are 8-33 at home this season. Take the Astros on the runline.