Cincinnati is 35-42 on the road and ends a nine-game road trip today in St. Louis. They've lost four of five, including twice as a favorite. Brady Singer is very good at home (3.07 ERA) but has a 4.99 ERA on the road. Meanwhile, St. Louis plays its third straight at home. They've won two of the last three, as an underdog of +159 and at even money. Starter Andre Pallante has a 2.65 ERA against the Reds this season in 17 innings, holding them to a .234 average. That includes a 6-1 win in his only home start against them. Play St. Louis.
This Pro Pick was released to clients on September 17, 2025 at 11:24AM ET.
Cincinnati at St. Louis
September 17, 2025
2 units on St. Louis +111 (moneyline) (risk 2 to return 4.22)
Result:
LOSS
LOSS
TAKE THE GUESSWORK OUT OF SPORTS BETTING
Get free MLB Picks
I pore over the data, injuries, news, and odds every morning.
You get the best bets delivered to your inbox.