Chicago at Kansas City

The White Sox are already 0-1 on the season and they are 12-26 on the road game against a left-handed starter. Chicago faces a strong southpaw in Kansas City's Danny Duffy, who has an electric fastball and solid curveball. The White Sox are just 5-14 in their last 19 road games. With Chris Sale out for the first portion of the regular season, the White Sox rotation has to move up a notch and Jose Quintana goes here. The White Sox are 10-25 in Quintana's last 35 starts vs. a team with a winning record. And last season Quintana was 0-3 against the Royals with a 4.88 ERA! Play the KC Royals.