Arizona was eliminated from postseason play with its 7-4 loss to San Diego on Friday night. Fernando Tatis Jr. hit a go-ahead grand slam in the fourth, and the Padres banged out 12 hits. They'll face Eduardo Rodriguez tonight, and he allowed four runs on eight hits in four innings in his one appearance against the Padres this season. He has a 4.91 ERA and a 1.56 WHIP in 2025. Rodriguez is 4-7 with a 5.94 ERA and a .310 opponent batting average in night games. Michael King comes off five shutout innings on four hits against the White Sox. San Diego has won six straight against the NL West, and Arizona has lost seven of Rodriguez's past eight starts after allowing at least five runs in their previous game. The Padres have won four of the past five meetings and five of their past six overall. Take the Padres.
This Pro Pick was released to clients on September 27, 2025 at 11:28AM ET.
Arizona at San Diego
September 27, 2025
1.5 units on San Diego -133 (moneyline) (risk 1.5 to return 2.63)
Result:
WIN
WIN
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