Minnesota Twins vs St. Louis Cardinals Betting Picks

Connor Prielipp entered the season with the tools of a future top-of-rotation starter, and through his first five big-league outings, he looked exactly that: 2.88 ERA, 29 strikeouts, and a WHIP under a run per inning. The league made adjustments, and Prielipp has gone 2-3 with a 6.57 ERA over his last five starts, including a three-start stretch where he surrendered 16 earned runs. He settled somewhat in his most recent outing, limiting Kansas City to two runs over four-plus innings, and the Twins need him to build on that today. Matthew Liberatore provides no comfort on the other side: a 4.48 ERA and 1.51 WHIP on a Cardinals rotation that rarely gives St. Louis a dominant afternoon. Minnesota's offense answered last night, rallying for three home runs in the eighth to take a 9-8 win and snap four straight losses to St. Louis in this series. At a coin-flip price, that kind of home power with a lineup that has already hit 82 home runs this season puts the Twins in the right spot. Back the Twins this afternoon.

Minnesota looks to salvage the final game of this three-game series and will start Bailey Ober, who was 12-9 with a 3.98 ERA last season with an improved changeup. The Cardinals haven't faced Ober since 2021. Andre Pallante starts for St. Louis and he finished 8-8 with a 3.78 ERA in 2024. He is mostly a ground-ball pitcher and Minnesota's big hitters need to find some holes after hitting the ball hard the first two games with nothing to show for it. Byron Buxton. Carlos Correa and Matt Wallner are heavily due to break out after each have eight hitless at-bats. The Cardinals have gone UNDER in Pallante's past six home starts and the Twins are 4-0 UNDER in Ober's past four Sunday starts. The UNDER is 6-0 in Pallante's past six starts against teams that scored two or fewer runs their previous game. Minnesota is still favored as it does have better overall talent. Take the Twins and the UNDER.

Minnesota will try to even the series after losing 5-3 in the season opener and the Twins will start Joe Ryan, who went 7-7 with a 3.60 ERA before suffering a shoulder injury last season. Erick Fedde goes for St. Louis after finishing 9-9 with a 3.30 ERA with the Chicago White Sox and the Cardinals in 2024. The Twins are determined to atone for a late-season collapse as they went 12-27 their final 39 games to miss the playoffs. Minnesota's two top hitters, Carlos Correa and Byron Buxton, look to bounce back from a combined 0-for-8 performance on Thursday when St. Louis jumped out to a 4-0 lead. Both bullpens gave up a combined total of two runs after the fifth inning on Opening Day. Take the Twins and the UNDER.