Pittsburgh sends Paul Skenes to the mound tonight — the reigning NL Cy Young winner, 75 strikeouts this season, a 2.89 ERA — and the market has priced this accordingly, installing the Pirates as road favorites. Spencer Arrighetti counters for Houston, and the numbers say the market has it backwards. Arrighetti is 7-1 with a 1.34 ERA, one of the best marks in baseball this season, carrying an Astros staff that has absorbed more catastrophic injury losses than any rotation should. Houston has also been banged up on offense. Carlos Correa is done for the year following ankle surgery. Jose Altuve is working his way back from an oblique strain. That injury toll is already priced into this number, which is why Arrighetti goes out as the underdog despite outperforming Skenes in every surface stat this season. The market is paying for Pittsburgh's record and Skenes' reputation. I'm taking advantage and backing the home side tonight. Take Houston.
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Pirates vs. Astros Betting Picks
Get Pirates vs. Astros betting picks, expert betting analysis, computer model picks, betting consensus data, matchup breakdowns, key betting angles, and the latest odds insights for today's Pirates vs. Astros game.
Public Consensus
Who was the public on? 63% of the public money was on Houston Astros to win on the moneyline. And, 82% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that Houston would win by a score of 5.6 to 4.7 with Houston winning on the moneyline, Pittsburgh winning on the runline and the game going OVER the total.
Final Score
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Public Consensus
Who was the public on? 63% of the public money was on Pittsburgh Pirates to win on the moneyline. And, 97% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that Pittsburgh would win by a score of 5.3 to 3.8 with Pittsburgh winning on the moneyline, Houston winning on the runline and the game going OVER the total.
Pro Picks
Pittsburgh at Houston
Final Score
Lines & Odds
Public Consensus
Who was the public on? 59% of the public money was on Houston Astros to win on the moneyline. And, 96% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that Houston would win by a score of 5.2 to 4.2 with Houston winning on the moneyline, Pittsburgh winning on the runline and the game going OVER the total.
Final Score
Lines & Odds
Public Consensus
Who was the public on? 73% of the public money was on Houston Astros to win on the moneyline. And, 67% of the bets were on the game to go UNDER the total.
Computer Predictions
My computer prediction for this game was that Houston would win by a score of 4.7 to 3.9 with Houston winning on the moneyline, Pittsburgh winning on the runline and the game going OVER the total.
Pro Picks
Houston at Pittsburgh
Houston comes off a 3-0 loss to the Pirates, but the Astros still have won seven of 10 while Pittsburgh is firmly in last place in the NL Central. Houston has gone UNDER four of five overall and six of seven on the road. The Pirates have stayed UNDER 11 of 14 home games and they are averaging only 3.18 runs per game in 2025. The Astros are 34-24 UNDER and the Pirates 38-23 UNDER overall this season. Pittsburgh is 0-11 in Mitch Keller's past 11 starts when pitching with five days rest and 0-8 when he starts after the Pirates allowed two or fewer runs their previous game. Framber Valdez has allowed only seven runs his past 37 innings and the Astros have won his past five starts. Pittsburgh hitters are batting just .200 with one homer in 60 at-bats against Valdez. Take the Astros to win, and bet the UNDER.
Final Score
Lines & Odds
Public Consensus
Who was the public on? 68% of the public money was on Houston Astros to win on the moneyline. And, 60% of the bets were on the game to go UNDER the total.
Computer Predictions
My computer prediction for this game was that Houston would win by a score of 4.5 to 4.4 with Houston winning on the moneyline, Pittsburgh winning on the runline and the game going UNDER the total.
Final Score
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