Stanford has fallen upon hard times with four straight 3-9 seasons, and the Cardinal has already lost two of three this season, although they did pull off a 30-20 upset over Boston College last week while taking advantage of three Eagles turnovers. Stanford is 1-6 ATS in its past seven road games and 1-9-2 ATS after totaling more than 200 yards rushing in its previous game. Also, the Cardinal are 0-4 ATS after allowing fewer than 100 rushing yards and they are 5-12-1 ATS their past 18 games. Eight of Stanford's past nine September games have gone UNDER, and Virginia has stayed UNDER six of eight at home. The Cardinal are 6-1-1 UNDER after yielding fewer than 100 rushing yards in their previous game. Virginia has covered four of five as a favorite, including covering a 31-point spread against FCS William & Mary last week. Chandler Morris and Daniel Kaelin combined to throw for 313 yards, and Harrison Waylee rushed for 151 yards on only 10 carries. Virginia is 8-0 ATS as a conference favorite of fewer than 18 points off a non-conference game. Take Virginia and the UNDER.
Previous Matchups & Picks
September 20, 2025 7:30pm ET
@
Stanford Cardinal
#371
Virginia Cavaliers
#372
Lines & Odds
+16.5 (-110)
ATS
-16.5 (-110)
+541
Moneyline
-785
OVER 48.5 (-105)
Total
UNDER 48.5 (-115)
Cardinal vs. Cavaliers Spread Picks
Get this week's Cardinal vs. Cavaliers point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Cardinal vs. Cavaliers.
Public Consensus
Who was the public on? 57% of the public bets were on Stanford Cardinal on the +16.5 ATS. And, 52% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that Virginia would win by a score of 29.7 to 18.5 with Virginia winning on the moneyline, Stanford winning on the spread and the game going UNDER the total.
Pro Picks
These Pro Picks were released to clients on September 18, 2025 at 10:19AM ET.
Stanford at Virginia
September 20, 2025
Final Score
1
2
3
4
F
Stanford Cardinal
7
7
6
0
20
Virginia Cavaliers
21
7
10
10
48
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