QB Steve Angeli tore his Achillies heel and is out for the season. Their passing game has gone from 8.4 ypa with Angeli, down to 6.4 ypa. with Collins. Collins should find some room to throw vs. SMU. The Mustangs have been awful against the pass allowing 7.9 ypa and 335 passing yards a game allowed. It's tough to cover a big number as we have here when your defense is not stopping opponents. This is the same line that Syracuse faced at Clemson, so is SMU that good? Syracuse actually won that game 34-21, so they are capeable. SMU has not beaten anyone good with their two wins coming against East Texas A&M, and Missouri St. and are failing to cover at -10 PPG. I like Syracuse.
Previous Matchups & Picks
October 4, 2025 3:30pm ET
@
Syracuse Orange
#387
SMU Mustangs
#388
Lines & Odds
+17.5 (-110)
ATS
-17.5 (-110)
+579
Moneyline
-856
OVER 57 (-110)
Total
UNDER 57 (-110)
Orange vs. Mustangs Spread Picks
Get this week's Orange vs. Mustangs point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Orange vs. Mustangs.
Public Consensus
Who was the public on? 59% of the public bets were on Syracuse Orange on the +17.5 ATS. And, 61% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that SMU would win by a score of 36.9 to 21.7 with SMU winning on the moneyline, Syracuse winning on the spread and the game going OVER the total.
Pro Picks
This Pro Pick was released to clients on October 02, 2025 at 11:55AM ET.
CFB
Syracuse at SMU
October 4, 2025
3:30 PM Eastern
Final Score
1
2
3
4
F
Syracuse Orange
0
3
0
15
18
SMU Mustangs 
3
21
0
7
31
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