Previous Matchups & Picks

September 26, 2026 12:00pm ET
@
Wake Forest Demon Deacons
Wake Forest Demon Deacons
#323
Louisville Cardinals
Louisville Cardinals
#324

Lines & Odds

+11.5 (-110)
ATS
-11.5 (-110)
+372
Moneyline
-478
OVER 57.5 (-110)
Total
UNDER 57.5 (-110)

Demon Deacons vs. Cardinals Spread Picks

Get this week's Demon Deacons vs. Cardinals point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Demon Deacons vs. Cardinals.

Public Consensus

Who was the public on? 51% of the public bets were on Louisville Cardinals on the -11.5 ATS. 98% of the public money was on Louisville Cardinals to win on the moneyline. And, 71% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Louisville would win by a score of 35.1 to 21.6 with Louisville winning on the moneyline and on the spread and the game going UNDER the total.

Pro Picks

This Pro Pick was released to clients on September 24, 2026 at 11:27AM ET.
img CFB

Wake Forest at Louisville

September 26, 2026
img12:00 PM Eastern

Both of these offenses have scored 38 or more in five of their combined six games, and I've had the total UNDER on each of these teams in the last two weeks and gotten run over both times, so I'm not pretending this is an easy call. What's different here is where it's being played. Louisville's defense has been a different team at home, allowing an average in the low 20s across its two games at L&N Stadium against a group that includes an ACC offense in SMU, with the one bad number coming on the road at Ole Miss. Wake Forest is walking into a true road environment against a team pushing for the ACC championship game, and its own offense came back to earth in its last outing, its lowest point total of the season. Two efficient passing attacks can still turn into a lower-scoring afternoon when one defense tightens up at home, and the other offense is coming off its quietest game. Go with the UNDER today.

Final Score

1
2
3
4
F
Wake Forest Demon Deacons img
3
21
3
3
30
Louisville Cardinals
7
14
6
0
27

CFB Pro Pick Results

Here’s how my Pro Picks are performing.

CFBCFB All Picks last 13.8 years
Wins
Losses
Units
2,411
2,205
+81.51
CFBCFB Max Plays last 9.8 years
Wins
Losses
Units
295
240
+69.66
CFBCFB All Playoff Picks last 17.1 years
Wins
Losses
Units
322
295
+52.15
CFBCFB Free Picks last 14.1 years
Wins
Losses
Units
155
117
+35.93
CFBCFB All Picks this season last 10 days
Wins
Losses
Units
1
0
+1.82
CFBCFB Between teams last 1 day
Wins
Losses
Units
1
0
+0.88
October 29, 2022 3:30pm ET
@
Wake Forest Demon Deacons
Wake Forest Demon Deacons
#137
Louisville Cardinals
Louisville Cardinals
#138

Lines & Odds

-3 (-110)
ATS
+3 (-110)
-160
Moneyline
+138
OVER 66.5 (-110)
Total
UNDER 66.5 (-110)

Public Consensus

Who was the public on? 66% of the public bets were on Wake Forest Demon Deacons on the -3 ATS. And, 62% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Wake Forest would win by a score of 33.7 to 30.4 with Wake Forest winning on the moneyline and on the spread and the game going UNDER the total.

Pro Picks

This Pro Pick was released to clients on October 26, 2023 at 8:56AM ET.
img CFB

Wake Forest at Louisville

October 29, 2022
img3:30 PM Eastern

Wake Forest is a 6-point loss to Clemson away from being unbeaten. This is a team that has been very offensive over the last couple of years. They will be up against Louisville who has held four opponents to 17 points or fewer on the season. The one big difference from this year's Wake Forest team is they are above average defensively. Louisville likes to run the ball and does so successfully. I would tend to believe they are going to try and run even more to keep the Wake offense off the field nd limit possessions in this game. Wake played an UNDER game last time on the field, and when they play UNDER their next game has also gone UNDER to a 71-43 ATS mark. I like the UNDER in this one.

Final Score

1
2
3
4
F
Wake Forest Demon Deacons
0
14
0
7
21
Louisville Cardinals img
6
7
35
0
48
October 2, 2021 12:30pm ET
@
Louisville Cardinals
Louisville Cardinals
#141
Wake Forest Demon Deacons
Wake Forest Demon Deacons
#142

Lines & Odds

+7 (-110)
ATS
-7 (-110)
+228
Moneyline
-271
OVER 64.5 (-110)
Total
UNDER 64.5 (-110)

Public Consensus

Who was the public on? 65% of the public bets were on Wake Forest Demon Deacons on the -7 ATS. And, 61% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Wake Forest would win by a score of 33.8 to 28.8 with Wake Forest winning on the moneyline, Louisville winning on the spread and the game going UNDER the total.

Final Score

1
2
3
4
F
Louisville Cardinals
10
7
0
17
34
Wake Forest Demon Deacons img
10
10
7
10
37
December 12, 2020 12:00pm ET
@
Wake Forest Demon Deacons
Wake Forest Demon Deacons
#113
Louisville Cardinals
Louisville Cardinals
#114

Lines & Odds

-1 (-115)
ATS
+1 (-105)
-120
Moneyline
+101
OVER 62 (-110)
Total
UNDER 62 (-110)

Public Consensus

Who was the public on? 51% of the public bets were on Wake Forest Demon Deacons on the -1 ATS. And, 59% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Louisville would win by a score of 35.1 to 31.0 with Louisville winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Wake Forest Demon Deacons
7
3
3
8
21
Louisville Cardinals img
0
21
7
17
45
October 12, 2019 7:30pm ET
@
Louisville Cardinals
Louisville Cardinals
#121
Wake Forest Demon Deacons
Wake Forest Demon Deacons
#122

Lines & Odds

+7 (-110)
ATS
-7 (-110)
+223
Moneyline
-265
OVER 65 (-110)
Total
UNDER 65 (-110)

Public Consensus

Who was the public on? 68% of the public bets were on Wake Forest Demon Deacons on the -7 ATS. And, 54% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Wake Forest would win by a score of 37.7 to 29.3 with Wake Forest winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Louisville Cardinals img
21
10
14
17
62
Wake Forest Demon Deacons
7
14
10
28
59

Get free CFB Picks

I pour over the data, injuries, news, and odds every morning. You get the best bets delivered to your inbox.