Previous Matchups & Picks

September 27, 2025 12:00pm ET
@
Louisville Cardinals
Louisville Cardinals
#135
Pittsburgh Panthers
Pittsburgh Panthers
#136

Lines & Odds

-3 (-110)
ATS
+3 (-110)
-153
Moneyline
+130
OVER 54.5 (-110)
Total
UNDER 54.5 (-110)

Cardinals vs. Panthers Spread Picks

Get this week's Cardinals vs. Panthers point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Cardinals vs. Panthers.

Public Consensus

Who was the public on? 51% of the public bets were on Louisville Cardinals on the -3 ATS. And, 53% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Louisville would win by a score of 30.7 to 25.2 with Louisville winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Louisville Cardinals img
0
17
3
14
34
Pittsburgh Panthers
17
10
0
0
27

CFB Pro Pick Results

Here’s how my Pro Picks are performing.

CFBCFB All Picks last 13.7 years
Wins
Losses
Units
2,344
2,139
+93.02
CFBCFB Max Plays last 9.1 years
Wins
Losses
Units
284
228
+73.57
CFBCFB All Playoff Picks last 17.1 years
Wins
Losses
Units
322
295
+52.15
CFBCFB Free Picks last 14.0 years
Wins
Losses
Units
152
113
+38.27
CFBCFB Free Picks this season last 7 days
Wins
Losses
Units
1
0
+1.39
CFBCFB Between teams last 1 day
Wins
Losses
Units
1
0
+1.82
November 23, 2024 4:00pm ET
@
Pittsburgh Panthers
Pittsburgh Panthers
#125
Louisville Cardinals
Louisville Cardinals
#126

Lines & Odds

+7 (-105)
ATS
-7 (-115)
+226
Moneyline
-269
OVER 57 (-110)
Total
UNDER 57 (-110)

Public Consensus

Who was the public on? 66% of the public bets were on Pittsburgh Panthers on the +7 ATS. And, 56% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Louisville would win by a score of 33.0 to 26.2 with Louisville winning on the moneyline, Pittsburgh winning on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Pittsburgh Panthers
0
0
7
2
9
Louisville Cardinals img
10
17
10
0
37
October 14, 2023 6:30pm ET
@
Louisville Cardinals
Louisville Cardinals
#145
Pittsburgh Panthers
Pittsburgh Panthers
#146

Lines & Odds

-7 (-110)
ATS
+7 (-110)
-295
Moneyline
+238
OVER 45 (-110)
Total
UNDER 45 (-110)

Public Consensus

Who was the public on? 58% of the public bets were on Louisville Cardinals on the -7 ATS. And, 63% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Louisville would win by a score of 29.4 to 21.1 with Louisville winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Louisville Cardinals
7
14
0
0
21
Pittsburgh Panthers img
7
7
17
7
38
October 22, 2022 8:00pm ET
@
Pittsburgh Panthers
Pittsburgh Panthers
#331
Louisville Cardinals
Louisville Cardinals
#332

Lines & Odds

+1.5 (-110)
ATS
-1.5 (-110)
+102
Moneyline
-122
OVER 55 (-110)
Total
UNDER 55 (-110)

Public Consensus

Who was the public on? 54% of the public bets were on Pittsburgh Panthers on the +1.5 ATS. And, 57% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Louisville would win by a score of 28.7 to 27.4 with Louisville winning on the moneyline, Pittsburgh winning on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on October 19, 2023 at 9:34AM ET.
img CFB

Pittsburgh at Louisville

October 22, 2022
img8:00 PM Eastern

Six of the past eight meetings have gone UNDER and the last one was in 2020 when Pittsburgh won 23-20 and it stayed UNDER by 10 points. The Panthers did beat Virginia Tech 45-29 two weeks ago, but they have gone UNDER four of their past five after scoring at least 40 points and they had a bye last week. Pitt racked up 326 rushing yards on 43 carries against the Hokies, but the Panthers basically have a one-dimensional offense and QB Kevon Slovis has struggled while replacing Kenny Pickett and they depended on Isreal Abanikanda's 320-yard, six-TD game to get past Virginia Tech. Louisville allows 22.3 points per game and it is #52 in the country in rushing yards allowed and the Cardinals obviously will zoom in on Abanikanda and Pitt's running game as long as the Panthers can't do much through the air. This is a high posted total. Take the UNDER as a Max Play

Final Score

1
2
3
4
F
Pittsburgh Panthers
7
0
3
0
10
Louisville Cardinals img
0
7
0
17
24
September 26, 2020 12:00pm ET
@
Louisville Cardinals
Louisville Cardinals
#401
Pittsburgh Panthers
Pittsburgh Panthers
#402

Lines & Odds

+3 (-115)
ATS
-3 (-105)
+122
Moneyline
-143
OVER 53.5 (-109)
Total
UNDER 53.5 (-109)

Public Consensus

Who was the public on? 55% of the public bets were on Louisville Cardinals on the +3 ATS. And, 54% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Pittsburgh would win by a score of 31.0 to 27.1 with Pittsburgh winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Louisville Cardinals
7
10
3
0
20
Pittsburgh Panthers img
13
7
3
0
23

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