Duke Blue Devils vs Syracuse Orange Point Spread Picks

Blue Devils vs. Orange Spread Picks

Get this week's Blue Devils vs. Orange point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Blue Devils vs. Orange.

Public Consensus

Who was the public on? 70% of the public bets were on Syracuse Orange on the +4 ATS. And, 52% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Duke would win by a score of 29.2 to 28.9, Syracuse winning on the spread and the game going UNDER the total.

Pro Picks

This Pro Pick was released to clients on September 25, 2025 at 12:13PM ET.

CFB

Duke at Syracuse

September 27, 2025

12:00 PM Eastern

Duke (1-3 ATS) got flattened by Illinois (45-19) and failed to cover in its only road game, losing at Tulane, 34-27. They survived last week against NC State, 45-33, despite allowing 535 yards. Tulane put up 426 yards on them, while Illinois had 419 yards. Duke has a good offense, but so does Syracuse with QB Steve Angeli (10 TDs, 2 INTs), averaging 424.3 total yards. Syracuse has one defeat, to No. 24 Tennessee, and comes off a 34-21 win at Clemson as a +17 underdog. Syracuse is on a 7-5-1 run, including 3-1-1 ATS at home. They're also on a 7-4 ATS run as a dog. Play Syracuse. 

Final Score

1

2

3

4

F

Duke Blue Devils

10

14

7

7

38

Syracuse Orange

3

0

0

0

3

Public Consensus

Who was the public on? 68% of the public bets were on Syracuse Orange on the +2.5 ATS. And, 50% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Duke would win by a score of 26.5 to 24.8 with Duke winning on the moneyline, Syracuse winning on the spread and the game going UNDER the total.

Final Score

1

2

3

4

F

Duke Blue Devils

10

14

6

8

38

Syracuse Orange

7

7

7

3

24

Public Consensus

Who was the public on? 60% of the public bets were on Duke Blue Devils on the -9 ATS. And, 55% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Duke would win by a score of 31.2 to 21.8 with Duke winning on the moneyline and on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on November 16, 2023 at 11:16AM ET.

CFB

Syracuse at Duke

November 16, 2019

4:00 PM Eastern

Syracuse has had a tough schedule and has had two weeks to prepare, off a bye. QB Tommy DeVito (15 TDs, five INTs) has had an excellent campaign and the Orange were expected to be very strong in 2019, coming off of a 10-win season. Syracuse is still alive for a bowl and faces a Duke team with a losing record, on a 1-4 SU/ATS skid. The offense has fallen apart, scoring 14, 17 and 7 points the last three games. The Blue Devils are on a 3-7 ATS run at home, plus 4-9 ATS after scoring less than 20 points in their previous game. Play Syracuse here as a Max Play.

Final Score

1

2

3

4

F

Syracuse Orange

14

0

21

14

49

Duke Blue Devils

0

6

0

0

6

Public Consensus

Who was the public on? 83% of the public bets were on Duke Blue Devils on the -4 ATS. 77% of the public money was on Duke Blue Devils to win on the moneyline. And, 61% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Duke would win by a score of 26.9 to 24.1 with Duke winning on the moneyline, Syracuse winning on the spread and the game going UNDER the total.

Final Score

1

2

3

4

F

Duke Blue Devils

3

7

0

17

27

Syracuse Orange

3

0

7

0

10