Deion Sanders lost a lot of talent at the skill positions last year to the NFL draft. Colorado has played a reasonably tough schedule, and enters this game at 2-3. They are young and improving, and almost pulled the upset last week vs. BYU where they lost a tough 24-21 decision. The TCU Horned Frogs dropped their first game of the season last week by 3 at Arizona St. TCU's running game is not good, and they generated 12 yards on 24 carries. The passing game is strong, but teams are starting to realize, play them with a light box, and have extra defenders for the passing game. I think Colorado is on the road to improvement, and this looks like too many points. Make the play on Colorado.
Previous Matchups & Picks
October 4, 2025 7:30pm ET
@
Colorado Buffaloes
#381
TCU Horned Frogs
#382
Lines & Odds
+13.5 (-110)
ATS
-13.5 (-110)
+406
Moneyline
-552
OVER 57 (-110)
Total
UNDER 57 (-110)
Buffaloes vs. Horned Frogs Spread Picks
Get this week's Buffaloes vs. Horned Frogs point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Buffaloes vs. Horned Frogs.
Public Consensus
Who was the public on? 66% of the public bets were on TCU Horned Frogs on the -13.5 ATS. And, 60% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that TCU would win by a score of 35.4 to 22.6 with TCU winning on the moneyline, Colorado winning on the spread and the game going OVER the total.
Pro Picks
This Pro Pick was released to clients on October 02, 2025 at 11:55AM ET.
CFB
Colorado at TCU
October 4, 2025
7:30 PM Eastern
Final Score
1
2
3
4
F
Colorado Buffaloes
0
14
0
7
21
TCU Horned Frogs 
0
14
0
21
35
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September 2, 2023 12:00pm ET
@
Colorado Buffaloes
#187
TCU Horned Frogs
#188
Lines & Odds
+21 (-110)
ATS
-21 (-110)
+667
Moneyline
-1083
OVER 63.5 (-110)
Total
UNDER 63.5 (-110)
Public Consensus
Who was the public on? 57% of the public bets were on TCU Horned Frogs on the -21 ATS. And, 58% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that TCU would win by a score of 43.6 to 23.3 with TCU winning on the moneyline, Colorado winning on the spread and the game going OVER the total.
Final Score
1
2
3
4
F
Colorado Buffaloes
7
10
14
14
45
TCU Horned Frogs
0
14
14
14
42
September 2, 2022 10:00pm ET
@
TCU Horned Frogs
#161
Colorado Buffaloes
#162
Lines & Odds
-13.5 (-110)
ATS
+13.5 (-110)
-543
Moneyline
+409
OVER 59.5 (-110)
Total
UNDER 59.5 (-110)
Public Consensus
Who was the public on? 55% of the public bets were on Colorado Buffaloes on the +13.5 ATS. And, 61% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that TCU would win by a score of 31.3 to 27.3 with TCU winning on the moneyline, Colorado winning on the spread and the game going UNDER the total.
Final Score
1
2
3
4
F
TCU Horned Frogs
0
7
10
21
38
Colorado Buffaloes
3
3
0
7
13
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