Previous Matchups & Picks

September 20, 2025 12:00pm ET
@
Syracuse Orange
Syracuse Orange
#327
Clemson Tigers
Clemson Tigers
#328

Lines & Odds

+16.5 (-110)
ATS
-16.5 (-110)
+543
Moneyline
-792
OVER 54.5 (-110)
Total
UNDER 54.5 (-110)

Orange vs. Tigers Spread Picks

Get this week's Orange vs. Tigers point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Orange vs. Tigers.

Public Consensus

Who was the public on? 64% of the public bets were on Syracuse Orange on the +16.5 ATS. And, 51% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Clemson would win by a score of 34.2 to 21.1 with Clemson winning on the moneyline, Syracuse winning on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on September 18, 2025 at 10:19AM ET.
img CFB

Syracuse at Clemson

September 20, 2025
img12:00 PM Eastern

Syracuse is averaging just 3.0 yards per rush. They needed overtime to down UConn, 27-20, as a 7-point favorite, rushing for 47 yards on 27 carries while turning it over twice. This is their second road game, losing at Tennessee with two more turnovers. The offense is 93rd in the country on third down (34.48%). Clemson's defense has kept them in games, but they have a losing record with an offense that is ranked 92nd in scoring (19.3 ppg) and 105th in total yards. QB Cade Klubnik has as many TDs as picks (3). The Tigers are 3-0 UNDER the total this season. Take Syracuse/Clemson UNDER the total. 

Final Score

1
2
3
4
F
Syracuse Orange img
10
14
10
0
34
Clemson Tigers
7
7
0
7
21

CFB Pro Pick Results

Here’s how my Pro Picks are performing.

CFBCFB All Picks last 13.7 years
Wins
Losses
Units
2,344
2,139
+93.02
CFBCFB Max Plays last 9.1 years
Wins
Losses
Units
284
228
+73.57
CFBCFB All Playoff Picks last 17.1 years
Wins
Losses
Units
322
295
+52.15
CFBCFB Free Picks last 14.0 years
Wins
Losses
Units
152
113
+38.27
CFBCFB Free Picks this season last 7 days
Wins
Losses
Units
1
0
+1.39
CFBCFB Between teams last 3.9 years
Wins
Losses
Units
3
0
+3.77
September 30, 2023 12:00pm ET
@
Clemson Tigers
Clemson Tigers
#125
Syracuse Orange
Syracuse Orange
#126

Lines & Odds

-7 (-115)
ATS
+7 (-110)
-298
Moneyline
+240
OVER 52 (-110)
Total
UNDER 52 (-110)

Public Consensus

Who was the public on? 64% of the public bets were on Syracuse Orange on the +7 ATS. And, 51% of the bets were on the game to go UNDER the total.

Computer Predictions

My computer prediction for this game was that Clemson would win by a score of 27.1 to 24.9 with Clemson winning on the moneyline, Syracuse winning on the spread.

Final Score

1
2
3
4
F
Clemson Tigers img
14
7
3
7
31
Syracuse Orange
7
0
0
7
14
October 22, 2022 12:00pm ET
@
Syracuse Orange
Syracuse Orange
#353
Clemson Tigers
Clemson Tigers
#354

Lines & Odds

+14 (-110)
ATS
-14 (-110)
+438
Moneyline
-620
OVER 50 (-110)
Total
UNDER 50 (-110)

Public Consensus

Who was the public on? 64% of the public bets were on Syracuse Orange on the +14 ATS. And, 54% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Clemson would win by a score of 29.1 to 22.0 with Clemson winning on the moneyline, Syracuse winning on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on October 19, 2023 at 9:34AM ET.
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Syracuse at Clemson

October 22, 2022
img12:00 PM Eastern

Clemson has had a strong reputation since Dabo Swinney arrived. Syracuse was really good once upon a time but hasn't been lately until this year. That has set up a line that is significantly padded toward the Tigers. Clemson has won 3 games by 10 points or fewer and that is not the Clemson we knew up until last year. The numbers tell the story. Clemson outgains opponents by 79 yards per game and 1.1 yards per play. Syracuse outgains opponents by 163 yards and 2 yards per play. That is to a schedule of teams that is pretty close to even. I actually think Syracuse could win this one, but will gladly take an over-flow in points. Make the play on Syracuse.

Final Score

1
2
3
4
F
Syracuse Orange
7
14
0
0
21
Clemson Tigers img
7
3
0
17
27
October 15, 2021 7:00pm ET
@
Clemson Tigers
Clemson Tigers
#115
Syracuse Orange
Syracuse Orange
#116

Lines & Odds

-13.5 (-105)
ATS
+13.5 (-115)
-552
Moneyline
+428
OVER 44 (-110)
Total
UNDER 44 (-110)

Public Consensus

Who was the public on? 65% of the public bets were on Syracuse Orange on the +13.5 ATS. And, 61% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Clemson would win by a score of 30.5 to 16.7 with Clemson winning on the moneyline and on the spread and the game going OVER the total.

Pro Picks

This Pro Pick was released to clients on October 12, 2023 at 10:06AM ET.
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Clemson at Syracuse

October 15, 2021
img7:00 PM Eastern

Clemson won last year's meeting, 47-21, but this is a different team that hasn't scored more than 21 points in four of its five games this season. The Tigers got by Boston College, 19-13, but they didn't cover as a 14.5-point favorite, and DJ Uiagalelei went only 13 of 28 for 207 yards and no touchdowns. Kobe Pace ran for 125 yards on 19 carries, including a 59-yard TD run for the Tigers. Syracuse suffered a tough overtime loss to Wake Forest after tying the game with a 28-yard TD pass to Sean Tucker with 21 seconds left in regulation. Garrett Shrader completed 15 of 27 for 160 yards and 2 TDs with no interceptions. He also ran for 178 yards on 29 carries with a touchdown. Syracuse actually prefers to get the running game going with Shrader and then take advantage of a bewildered opposing defense on passing downs. Clemson is 0-6 ATS its last six games, and the underdog is 5-2 ATS the past seven meetings. Syracuse has covered five of its last six home games and six of seven overall as a dog. Play Syracuse.

Final Score

1
2
3
4
F
Clemson Tigers img
0
14
0
3
17
Syracuse Orange
0
7
0
7
14
October 24, 2020 12:00pm ET
@
Syracuse Orange
Syracuse Orange
#325
Clemson Tigers
Clemson Tigers
#326

Lines & Odds

+47 (-110)
ATS
-47 (-110)
+50000
Moneyline
-150000
OVER 63.5 (-110)
Total
UNDER 63.5 (-110)

Public Consensus

Who was the public on? 54% of the public bets were on Syracuse Orange on the +47 ATS. And, 77% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Clemson would win by a score of 54.1 to 9.6 with Clemson winning on the moneyline, Syracuse winning on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Syracuse Orange
0
14
7
0
21
Clemson Tigers img
17
10
7
13
47

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