Previous Matchups & Picks

November 14, 2025 7:30pm ET
@
Clemson Tigers
Clemson Tigers
#315
Louisville Cardinals
Louisville Cardinals
#316

Lines & Odds

+1.5 (-110)
ATS
-1.5 (-110)
+104
Moneyline
-124
OVER 51 (-110)
Total
UNDER 51 (-110)

Tigers vs. Cardinals Spread Picks

Get this week's Tigers vs. Cardinals point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between Tigers vs. Cardinals.

Public Consensus

Who was the public on? 64% of the public bets were on Louisville Cardinals on the -1.5 ATS. And, 64% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Louisville would win by a score of 27.8 to 25.6 with Louisville winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Clemson Tigers img
3
7
3
7
20
Louisville Cardinals
3
6
10
0
19

CFB Pro Pick Results

Here’s how my Pro Picks are performing.

CFBCFB All Picks last 13.7 years
Wins
Losses
Units
2,344
2,139
+93.02
CFBCFB Max Plays last 9.1 years
Wins
Losses
Units
284
228
+73.57
CFBCFB All Playoff Picks last 17.1 years
Wins
Losses
Units
322
295
+52.15
CFBCFB Free Picks last 14.0 years
Wins
Losses
Units
152
113
+38.27
CFBCFB Free Picks this season last 7 days
Wins
Losses
Units
1
0
+1.39
November 2, 2024 7:30pm ET
@
Louisville Cardinals
Louisville Cardinals
#323
Clemson Tigers
Clemson Tigers
#324

Lines & Odds

+11 (-110)
ATS
-11 (-115)
+328
Moneyline
-420
OVER 62.5 (-110)
Total
UNDER 62.5 (-110)

Public Consensus

Who was the public on? 68% of the public bets were on Clemson Tigers on the -11 ATS. And, 62% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Clemson would win by a score of 36.6 to 24.6 with Clemson winning on the moneyline and on the spread and the game going UNDER the total.

Final Score

1
2
3
4
F
Louisville Cardinals img
3
14
9
7
33
Clemson Tigers
7
0
0
14
21
November 12, 2022 3:35pm ET
@
Louisville Cardinals
Louisville Cardinals
#155
Clemson Tigers
Clemson Tigers
#156

Lines & Odds

+7 (-115)
ATS
-7 (-110)
+219
Moneyline
-270
OVER 51.5 (-110)
Total
UNDER 51.5 (-110)

Public Consensus

Who was the public on? 58% of the public bets were on Clemson Tigers on the -7 ATS. And, 54% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Clemson would win by a score of 30.6 to 23.0 with Clemson winning on the moneyline and on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Louisville Cardinals
0
7
3
6
16
Clemson Tigers img
10
7
7
7
31
November 6, 2021 7:30pm ET
@
Clemson Tigers
Clemson Tigers
#329
Louisville Cardinals
Louisville Cardinals
#330

Lines & Odds

-3.5 (-110)
ATS
+3.5 (-110)
-178
Moneyline
+155
OVER 46.5 (-110)
Total
UNDER 46.5 (-110)

Public Consensus

Who was the public on? 57% of the public bets were on Louisville Cardinals on the +3.5 ATS. And, 56% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Clemson would win by a score of 25.8 to 22.8 with Clemson winning on the moneyline, Louisville winning on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Clemson Tigers img
7
10
0
13
30
Louisville Cardinals
14
3
7
0
24
October 19, 2019 12:00pm ET
@
Clemson Tigers
Clemson Tigers
#321
Louisville Cardinals
Louisville Cardinals
#322

Lines & Odds

-24.5 (-110)
ATS
+24.5 (-110)
-3177
Moneyline
+1329
OVER 62 (-102)
Total
UNDER 62 (-108)

Public Consensus

Who was the public on? 62% of the public bets were on Clemson Tigers on the -24.5 ATS. And, 70% of the bets were on the game to go OVER the total.

Computer Predictions

My computer prediction for this game was that Clemson would win by a score of 43.0 to 20.4 with Clemson winning on the moneyline, Louisville winning on the spread and the game going OVER the total.

Final Score

1
2
3
4
F
Clemson Tigers img
3
14
7
21
45
Louisville Cardinals
0
3
0
7
10

Get free CFB Picks

I pour over the data, injuries, news, and odds every morning. You get the best bets delivered to your inbox.