Charlotte brings its 1-3 record to Florida to take on the South Florida Bulls. The only opponent that Charlotte beat was Monmouth, which is in the FCS, but they gave up 410 passing yards in that game. They are averaging just 10.3 PPG against their three FBS opponents. South Florida has beaten Boise State and Florida. They held them to a combined 23 points. Their only loss was to Miami, FL. I don't think this is a game where we see the best version of South Florida. The issue on the other side is that Charlotte can't move the ball and is unlikely to score a touchdown in this game. They haven't given up more than 34 points in a game all season. I like the UNDER.
Previous Matchups & Picks
October 3, 2025 7:00pm ET
@
Charlotte 49ers
#305
South Florida Bulls
#306
Lines & Odds
+28 (-110)
ATS
-28 (-110)
+1706
Moneyline
-6337
OVER 54.5 (-110)
Total
UNDER 54.5 (-110)
49ers vs. Bulls Spread Picks
Get this week's 49ers vs. Bulls point spread picks, including expert ATS picks, computer model projections, betting consensus trends, matchup analysis, key wagering angles, and the latest odds insights for the upcoming game between 49ers vs. Bulls.
Public Consensus
Who was the public on? 69% of the public bets were on South Florida Bulls on the -28 ATS. And, 62% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that South Florida would win by a score of 38.6 to 14.7 with South Florida winning on the moneyline, Charlotte winning on the spread and the game going UNDER the total.
Pro Picks
This Pro Pick was released to clients on October 02, 2025 at 11:55AM ET.
CFB
Charlotte at South Florida
October 3, 2025
7:00 PM Eastern
Final Score
1
2
3
4
F
Charlotte 49ers
0
7
3
16
26
South Florida Bulls 
23
10
0
21
54
CFB Pro Pick Results
Here’s how my Pro Picks are performing.
CFBCFB
All Picks last 13.7 years
Wins
Losses
Units
2,344
2,139
+93.02
CFBCFB
Max Plays last 9.1 years
Wins
Losses
Units
284
228
+73.57
CFBCFB
All Playoff Picks last 17.1 years
Wins
Losses
Units
322
295
+52.15
CFBCFB
Free Picks last 14.0 years
Wins
Losses
Units
152
113
+38.27
CFBCFB
Free Picks this season last 7 days
Wins
Losses
Units
1
0
+1.39
November 16, 2024 3:30pm ET
@
South Florida Bulls
#337
Charlotte 49ers
#338
Lines & Odds
+1.5 (-110)
ATS
-1.5 (-110)
-101
Moneyline
-119
OVER 53.5 (-120)
Total
UNDER 53.5 (+100)
Public Consensus
Who was the public on? 63% of the public bets were on South Florida Bulls on the +1.5 ATS. And, 50% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that South Florida would win by a score of 26.4 to 25.5 with South Florida winning on the moneyline and on the spread and the game going UNDER the total.
Final Score
1
2
3
4
F
South Florida Bulls
7
7
31
14
59
Charlotte 49ers
7
3
7
7
24
November 25, 2023 7:30pm ET
@
Charlotte 49ers
#171
South Florida Bulls
#172
Lines & Odds
+7 (-110)
ATS
-7 (-110)
+227
Moneyline
-277
OVER 57 (-110)
Total
UNDER 57 (-110)
Public Consensus
Who was the public on? 76% of the public bets were on South Florida Bulls on the -7 ATS. And, 52% of the bets were on the game to go OVER the total.
Computer Predictions
My computer prediction for this game was that South Florida would win by a score of 30.7 to 25.9 with South Florida winning on the moneyline, Charlotte winning on the spread and the game going UNDER the total.
Final Score
1
2
3
4
F
Charlotte 49ers
7
0
7
0
14
South Florida Bulls
7
14
20
7
48
Get free CFB Picks
I pour over the data, injuries, news, and odds every morning. You get the best bets delivered to your inbox.
Get a top-rated pick every day.