Charlotte 49ers vs SMU Mustangs Point Spread Picks

Charlotte has had a tough schedule but comes off a 22-7 loss at No. 25 Florida as a +28 underdog. They also covered as a big dog at Maryland. SMU is a huge favorite despite going 7-5 last year and 2-2 this season. The Mustangs lost star QB Tanner Mordecai in the offseason, transferring to Wisconsin. They've used four quarterbacks already and second-leading rusher L.J. Johnson Jr. (ankle) is questionable to play. The defense is allowing 25 points per game (the same as last season) and is 73rd in the country in third-down defense (40.91%) and 55th in total defense. SMU is 28-46 ATS against teams that allow 5.9 yards per play, plus 27-45 ATS versus pass defenses that give up 250+ passing yards per contest. With SMU 47-72 ATS off a road loss, back the big underdog. Play Charlotte.